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炎症和免疫细胞在血流限制训练适应中的作用:综述

The Role of Inflammation and Immune Cells in Blood Flow Restriction Training Adaptation: A Review.

作者信息

Rossi Fabrício Eduardo, de Freitas Marcelo Conrado, Zanchi Nelo Eidy, Lira Fábio Santos, Cholewa Jason M

机构信息

Exercise and Immunometabolism Research Group, Department of Physical Education, São Paulo State University (UNESP), Presidente Prudente, Brazil.

Skeletal Muscle Assessment Laboratory, Department of Physical Education, School of Technology and Sciences, São Paulo State University, Presidente Prudente, Brazil.

出版信息

Front Physiol. 2018 Oct 9;9:1376. doi: 10.3389/fphys.2018.01376. eCollection 2018.

DOI:10.3389/fphys.2018.01376
PMID:30356748
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6189414/
Abstract

Blood flow restriction (BFR) combined with low-intensity strength training has been shown to increase skeletal muscle mass and strength in a variety of populations. BFR results in a robust metabolic stress which is hypothesized to induce muscle growth via increased recruitment of fast-twitch muscle fibers, a greater endocrine response, and/or enhancing the cellular swelling contribution to the hypertrophic process. Following exercise, neutrophils are the first immune cells to initiate the tissue remodeling process via several mechanisms including an increased production of cytokines and recruitment of monocytes/macrophages, which facilitate the phagocytosis of foreign particles, the differentiation of myoblasts, and the formation of new myotubes. Thus, the purpose of this review was to discuss the mechanisms through which metabolic stress and immune cell recruitment may induce skeletal muscle remodeling following BFR strength training.

摘要

血流限制(BFR)与低强度力量训练相结合已被证明可增加各类人群的骨骼肌质量和力量。BFR会导致强烈的代谢应激,据推测,这种应激通过增加快肌纤维的募集、更大的内分泌反应和/或增强细胞肿胀对肥大过程的作用来诱导肌肉生长。运动后,中性粒细胞是首批通过多种机制启动组织重塑过程的免疫细胞,这些机制包括增加细胞因子的产生以及募集单核细胞/巨噬细胞,从而促进异物吞噬、成肌细胞分化和新肌管的形成。因此,本综述的目的是探讨代谢应激和免疫细胞募集在BFR力量训练后诱导骨骼肌重塑的机制。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aeea/6189414/656c92550707/fphys-09-01376-g0003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aeea/6189414/f9a1bb98cdd7/fphys-09-01376-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aeea/6189414/0b6bbff521e0/fphys-09-01376-g0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aeea/6189414/656c92550707/fphys-09-01376-g0003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aeea/6189414/f9a1bb98cdd7/fphys-09-01376-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aeea/6189414/0b6bbff521e0/fphys-09-01376-g0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aeea/6189414/656c92550707/fphys-09-01376-g0003.jpg

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Muscle as a paracrine and endocrine organ.肌肉作为一种旁分泌和内分泌器官。
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