Islas-Fabila Paloma, Bonilla-Jaime Herlinda, Roldán-Santiago Patricia, de la Cruz-Cruz Luis Alberto, Limón-Morales Ofelia, Jiménez-Collado Carlos Antonio, Orozco-Gregorio Héctor
Programa de Doctorado en Ciencias Biológicas y de la Salud, Universidad Autónoma Metropolitana, Ciudad de México 09340, Mexico.
Departamento de Biología de la Reproductiva, Universidad Autónoma Metropolitana, Ciudad de México 09340, Mexico.
Animals (Basel). 2025 Feb 20;15(5):619. doi: 10.3390/ani15050619.
The objective of this study was to evaluate the prophylactic effect of thiamine pyrophosphate (TPP) on the vitality scores of piglets based on their behavior and survival. A total of 149 piglets born from 15 multiparous sows were evaluated. The sows were randomly divided into two groups, control and TPP, with treatments administered 24 and 12 h before the expected farrowing date. The duration of farrowing was recorded. Furthermore, for all newborns, the Apgar vitality scale, teat suckling, newborn weight and weight at weaning, piglet vitality based on behavior (at birth and at 24 h), and skin temperature (at birth and at 24 h) were evaluated. The results indicated that the sows treated with TPP presented a lower farrowing duration ( = 0.0060) and their piglets exhibited a higher percentage in the piglet vitality-based behavior score (>50%). In addition, the newborn piglets of TPP-treated sows, which exhibited higher scores in behavior parameters, also displayed higher scores (>80%) in the Apgar vitality scale (>8), suckled on the teat for longer periods of time, and had higher daily weight gain ( < 0.0001). Our findings suggest that administering TPP at the end of gestation may shorten labor while also increasing the vitality of newborns. Therefore, it could be considered that, in practice, the administration of this treatment could have an impact on the energy that sows need during the farrowing process for the initiation of uterine contractions and abdominal effort. Therefore, this treatment could have an impact on the productivity and well-being of sows with a history of dystocic farrowing, which can increase the incidence of endometritis, vulvar discharge, placental retention, or mastitis-metritis-agalactia syndrome-alterations that can result in the reduced growth of piglets and a higher mortality before weaning. Therefore, the application of this treatment could not only reduce the probability of sows presenting these problems but perhaps also increase the probability of their offspring surviving in the first days after birth.
本研究的目的是基于仔猪的行为和存活情况，评估硫胺素焦磷酸（TPP）对仔猪活力评分的预防效果。对15头经产母猪所生的149头仔猪进行了评估。母猪被随机分为两组，即对照组和TPP组，在预计分娩日期前24小时和12小时进行处理。记录分娩持续时间。此外，对所有新生仔猪评估了阿氏活力评分、吮乳情况、出生体重和断奶体重、基于行为的仔猪活力（出生时和24小时时）以及皮肤温度（出生时和24小时时）。结果表明，用TPP处理的母猪分娩持续时间较短（ = 0.0060），其仔猪在基于行为的仔猪活力评分中比例较高（>50%）。此外，经TPP处理的母猪所生的新生仔猪在行为参数上得分较高，在阿氏活力评分（>8）中得分也较高（>80%），吮乳时间更长，日增重更高（ < 0.0001）。我们的研究结果表明，在妊娠末期给予TPP可能会缩短产程，同时提高新生仔猪的活力。因此，可以认为，在实际操作中，这种处理可能会影响母猪在分娩过程中启动子宫收缩和腹部用力所需的能量。因此，这种处理可能会对有难产史的母猪的生产力和健康产生影响，难产会增加子宫内膜炎、外阴流出物、胎盘滞留或乳腺炎-子宫炎-无乳综合征等疾病的发生率，这些疾病会导致仔猪生长减缓以及断奶前死亡率升高。因此，应用这种处理不仅可以降低母猪出现这些问题的概率，还可能提高其后代在出生后最初几天存活的概率。
