de Carvalho Vilar Mariana Dantas, Coutinho Karla Monica Dantas, de Lima Vale Sancha Helena, Dourado Junior Mario Emilio Teixeira, de Medeiros Gidyenne Christine Bandeira Silva, Piuvezam Grasiela, Brandao-Neto Jose, Leite-Lais Lucia
Postgraduate Program in Health Sciences, Federal University of Rio Grande do Norte, Natal 59012-300, Brazil.
Laboratory of Technological Innovation in Health (LAIS), Federal University of Rio Grande do Norte, Natal 59012-300, Brazil.
Nutrients. 2025 Feb 24;17(5):782. doi: 10.3390/nu17050782.
: This study is a systematic review of guidelines that aims to synthesize evidence-based recommendations to support appropriate nutritional management for patients with amyotrophic lateral sclerosis (ALS). : PubMed/MEDLINE, Embase, Scopus, SciELO, Web of Science, LILACS, ScienceDirect, and Google Scholar were searched for records published up to July 2024. Clinical practice guidelines addressing any aspect of nutritional intervention in ALS were included. No language or country of publication restrictions were applied. Data extraction was performed by two independent reviewers. The methodological quality of the reports was assessed using the AGREE II instrument. Discrepancies were resolved by consensus. : The findings and main recommendations were summarized narratively. A total of 837 records were identified, and 11 were included in this review. The overall AGREE II scores for the included studies ranged from 3 to 7. The summary of nutritional recommendations was organized into topics: (1) dysphagia, (2) nutritional assessment, (3) energy, (4) protein, (5) supplementation, and (6) percutaneous endoscopic gastrostomy (PEG). This review summarizes relevant and updated nutritional recommendations to maintain or restore the nutritional status of patients with ALS, contributing to their quality of life and survival time. : These nutritional recommendations will help health professionals and caregivers to implement and standardize nutritional care according to evidence-based practice in ALS. PROSPERO registration number CRD42021233088.
本研究是一项对指南的系统评价，旨在综合基于证据的建议，以支持对肌萎缩侧索硬化症（ALS）患者进行适当的营养管理。在PubMed/MEDLINE、Embase、Scopus、SciELO、Web of Science、LILACS、ScienceDirect和谷歌学术中检索截至2024年7月发表的记录。纳入涉及ALS营养干预任何方面的临床实践指南。不设语言或发表国家限制。由两名独立评审员进行数据提取。使用AGREE II工具评估报告的方法学质量。分歧通过协商解决。研究结果和主要建议进行了叙述性总结。共确定了837条记录，本综述纳入了11条。纳入研究的AGREE II总体得分在3至7分之间。营养建议总结分为以下主题：（1）吞咽困难，（2）营养评估，（3）能量，（4）蛋白质，（5）补充剂，（6）经皮内镜下胃造口术（PEG）。本综述总结了相关且最新的营养建议，以维持或恢复ALS患者的营养状况，改善其生活质量和生存时间。这些营养建议将帮助卫生专业人员和护理人员根据ALS的循证实践实施和规范营养护理。PROSPERO注册号CRD42021233088。
