Luo Chunfeng, Song Yonghong, Xia Luoyuan, Liu Minxuan, Feng Hao, Xiao Licheng, Xu Ming, Cai Xiangyin, Cui Jianye, Xiang Rong, Yang Jihu, Kan Wei, Shen Yanli, Ma Yuanlian, Zeng Zhanhao, Liu Baohan, Tao Yulian, Yu Huimin, Sun Yi, Wang Xiaorun, Jiang Jiafu
Department of Epidemiology and Health Statistics, School of Public Health, Anhui Medical University, Hefei 230032, China.
State Key Laboratory of Pathogen and Biosecurity, Academy of Military Medical Sciences, Beijing 100071, China.
Biosaf Health. 2024 Nov 19;6(6):361-368. doi: 10.1016/j.bsheal.2024.11.005. eCollection 2024 Dec.
Recently, there has been a continuous stream of reports on emerging tick-borne pathogens affecting humans. Qinghai Province, located in the northweastern region, is one of China's major pastoral areas, providing a suitable environment for ticks' survival and transmitting tick-borne pathogens. Here, we collected 560 free-living and parasitic ticks from 11 locations in Qinghai Province using the flag-drag method or tweezers, identifying them as belonging to 4 species of ticks. The overall positivity rate for tick-borne pathogens was 51.61 %, comprising (34.64 %), (5.00 %), (2.14 %), sensu lato (BBSL) (7.50 %), (0.18 %), and (5.89 %). Sequencing revealed the presence of 7 species of , 4 species of , 2 species of , 2 species of BBSL, 1 species of and 3 species of . Among the ticks, 6.43 % were co-infected with 2 pathogens, while 0.36 % exhibited co-infection with 3 pathogens. Significant correlations ( < 0.05) were observed between the prevalence of tick-borne pathogens and factors including tick species, sex, developmental stages, parasitic status, and blood-feeding status. The results highlight the diverse distribution of tick-borne pathogens in Qinghai Province, posing a significant threat to both local animal husbandry and human health. It underscores the need to enhance systematic monitoring of tick-borne pathogens in the local population and livestock.
最近，关于影响人类的新兴蜱传病原体的报道不断涌现。青海省位于中国东北部，是中国主要牧区之一，为蜱虫的生存和传播蜱传病原体提供了适宜的环境。在此，我们采用拖旗法或镊子法从青海省11个地点采集了560只游离蜱和寄生蜱，鉴定出它们属于4种蜱虫。蜱传病原体的总体阳性率为51.61%，包括（34.64%）、（5.00%）、（2.14%）、狭义（BBSL）（7.50%）、（0.18%）和（5.89%）。测序结果显示存在7种、4种、2种、2种BBSL、1种和3种。在蜱虫中，6.43%被两种病原体共同感染，而0.36%表现出三种病原体的共同感染。观察到蜱传病原体的流行率与蜱虫种类、性别、发育阶段、寄生状态和吸血状态等因素之间存在显著相关性（<0.05）。结果突出了青海省蜱传病原体的多样分布，对当地畜牧业和人类健康都构成了重大威胁。这强调了加强对当地人群和家畜中蜱传病原体系统监测的必要性。
