使用蒙特卡罗模拟研究用于内剂量学的典型3D打印材料的组织等效性。
Investigation of the tissue equivalence of typical 3D-printing materials for application in internal dosimetry using monte carlo simulations.
作者信息
Karadeniz-Yildirim Ayse, Tanyildizi-Kokkulunk Handan
机构信息
Opticianry Program, Istanbul Aydın University, Florya, Bakirkoy, Istanbul, 34295, Turkey.
Radiotherapy Program, Altınbaş University, Kartaltepe Dist, Bakirkoy, Istanbul, 34147, Turkey.
出版信息
Phys Eng Sci Med. 2025 Mar 13. doi: 10.1007/s13246-025-01532-2.
UNLABELLED
This study evaluates the dosimetric accuracy of PLA and ABS 3D-printed phantoms compared to real tissues using Monte Carlo simulations in radionuclide therapy.
MATERIALS AND METHODS
A phantom representing average liver and lung volumes, with a 10 mm tumor mimic in the liver, was simulated for radioembolization using 1 mCi Tc-99 m and 1 mCi Y-90. The dose distribution (DD) was compared across PLA, ABS, and real organ densities.
RESULTS
For Tc-99 m, PLA showed a + 5.6% DD difference in the liver, and ABS showed - 35.3% and - 40.9% differences in the lungs. For Y-90, PLA had a + 1.7% DD difference in the liver, while ABS showed - 34.2% and - 34.9% differences in the lungs.
CONCLUSION
In MC simulation, PLA is suitable for representing high-density tissues, while ABS is appropriate for simulating moderately low-density tissues.
未标注
本研究使用蒙特卡罗模拟评估放射性核素治疗中聚乳酸（PLA）和丙烯腈-丁二烯-苯乙烯共聚物（ABS）3D打印体模与真实组织相比的剂量测定准确性。
材料与方法
模拟一个代表平均肝脏和肺体积的体模，肝脏中有一个10毫米的模拟肿瘤，使用1毫居里的锝-99m和1毫居里的钇-90进行放射性栓塞模拟。比较了聚乳酸、丙烯腈-丁二烯-苯乙烯共聚物和真实器官密度下的剂量分布（DD）。
结果
对于锝-99m，聚乳酸在肝脏中的剂量分布差异为+5.6%，丙烯腈-丁二烯-苯乙烯共聚物在肺中的差异为-35.3%和-40.9%。对于钇-90，聚乳酸在肝脏中的剂量分布差异为+1.7%，而丙烯腈-丁二烯-苯乙烯共聚物在肺中的差异为-34.2%和-34.9%。
结论
在蒙特卡罗模拟中，聚乳酸适用于代表高密度组织，而丙烯腈-丁二烯-苯乙烯共聚物适用于模拟中等低密度组织。
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