Insights from 40 years of educational research: honoring Jeroen van Merriënboer.

Simulation-based education in healthcare has advanced significantly, yet a persistent gap remains between educational science and healthcare simulation research. The late Jeroen van Merriënboer's extensive work in educational science provides valuable guidance for bridging this gap. Four key insights from his research can serve as a strong theoretical bedrock for educators and researchers aiming to design more effective and cohesive simulation-based learning experiences: (1) integrating learning in both simulated and real environments to improve transfer, (2) offering targeted learner support that evolves with expertise, (3) embracing the complexity of educational practice and avoiding one-size-fits-all solutions, and (4) embedding domain-general skills within specific disciplines. Championing these insights may catalyze more theory-informed practice and research in healthcare simulation. Nevertheless, applying these principles in practice remains a challenge, highlighting the need for further research into the "how"-specifically how to interconnect learning environments, adapt instruction to diverse needs, integrate theory with practice, and combine the teaching of domain-general and domain-specific skills.