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在患有慢性疼痛的医用大麻患者中,在大麻影响下工作。

Working under the influence of cannabis amongst medical cannabis patients with chronic pain.

作者信息

Lee Carol A, Tomlinson Devin C, Bohnert Kipling M, Bonar Erin E, Coughlin Lara N, Ilgen Mark A

机构信息

Department of Psychiatry, Addiction Center, University of Michigan, Ann Arbor, Michigan, USA.

Department of Epidemiology and Biostatistics, Michigan State University, East Lansing, Michigan, USA.

出版信息

Am J Addict. 2025 Jul;34(4):415-421. doi: 10.1111/ajad.70028. Epub 2025 Mar 14.

DOI:10.1111/ajad.70028
PMID:40084646
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12182713/
Abstract

BACKGROUND AND OBJECTIVES

Cannabis use is increasing in the United States, and, on average, those consuming medical cannabis report more frequent cannabis use than those who use recreationally. The present analyses focus on the prevalence and correlates of working under the influence of cannabis (WUIC) amongst individuals with chronic pain who use cannabis medically.

METHODS

Adults were recruited from medical cannabis certification clinics in Michigan and individuals who were employed in the past 6 months were included in the analytic sample (N = 362). Unadjusted and adjusted logistic regressions were estimated to examine factors associated with WUIC. Descriptive analyses examined WUIC by types of employment.

RESULTS

WUIC was reported by 34% (n = 123) of employed medical cannabis patients. After adjusting for other factors, older age and having episodes of 6+ drinks were significantly associated with lower odds of WUIC. History of driving under the influence of cannabis, reporting three+ hours high on cannabis per day, and using 0.5 oz+ of cannabis per week were all significantly associated with higher odds of WUIC.

DISCUSSION AND CONCLUSIONS

Amongst individuals who use cannabis for pain and are in the workforce, WUIC is relatively common. This may be particularly concerning in jobs that are safety-sensitive. Prevention efforts for WUIC might focus on those who use cannabis several times per day and might consider how to balance the needs for pain management with workplace-related roles.

SCIENTIFIC SIGNIFICANCE

The current study extends knowledge around the prevalence and characteristics of individuals using medical cannabis who engage in WUIC.

摘要

背景与目的

在美国,大麻的使用呈上升趋势,而且平均而言,使用医用大麻的人报告的大麻使用频率高于娱乐性使用者。本分析聚焦于医用大麻使用者中,在大麻影响下工作(WUIC)的患病率及其相关因素,这些使用者患有慢性疼痛。

方法

从密歇根州的医用大麻认证诊所招募成年人,分析样本纳入过去6个月内有工作的个体(N = 362)。估计未调整和调整后的逻辑回归,以检验与WUIC相关的因素。描述性分析按就业类型检查WUIC情况。

结果

34%(n = 12)的在职医用大麻患者报告有WUIC情况。在调整其他因素后,年龄较大以及有6杯及以上饮酒经历与较低的WUIC几率显著相关。有大麻影响下驾驶的历史、报告每天吸食大麻3小时以上以及每周使用0.5盎司及以上大麻均与较高的WUIC几率显著相关。

讨论与结论

在因疼痛而使用大麻且有工作的人群中,WUIC相对常见。在对安全敏感的工作中,这可能尤其令人担忧。针对WUIC的预防措施可能应关注那些每天多次使用大麻的人,并可能需要考虑如何在疼痛管理需求与工作场所职责之间取得平衡。

科学意义

本研究扩展了关于从事WUIC的医用大麻使用者的患病率和特征的知识。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0784/12182713/6141dc24f0d5/AJAD-34-415-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0784/12182713/6141dc24f0d5/AJAD-34-415-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0784/12182713/6141dc24f0d5/AJAD-34-415-g001.jpg

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本文引用的文献

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Ann Intern Med. 2024 Apr;177(4):458-466. doi: 10.7326/M23-2811. Epub 2024 Apr 9.
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Prevalence of Cannabis Use Disorder and Reasons for Use Among Adults in a US State Where Recreational Cannabis Use Is Legal.美国一州成年人中娱乐用大麻合法化背景下大麻使用障碍的流行率和使用原因。
JAMA Netw Open. 2023 Aug 1;6(8):e2328934. doi: 10.1001/jamanetworkopen.2023.28934.
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U.S. Trends in Registration for Medical Cannabis and Reasons for Use From 2016 to 2020 : An Observational Study.
2016 年至 2020 年美国医用大麻登记趋势及使用原因:一项观察性研究。
Ann Intern Med. 2022 Jul;175(7):945-951. doi: 10.7326/M22-0217. Epub 2022 Jun 14.
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Trends over time in adult cannabis use: A review of recent findings.成人使用大麻的时间趋势:近期研究结果综述。
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Subst Use Misuse. 2020;55(11):1733-1745. doi: 10.1080/10826084.2020.1759643. Epub 2020 May 22.
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Driving under the influence of cannabis among medical cannabis patients with chronic pain.慢性疼痛医用大麻患者中受大麻影响下驾驶。
Drug Alcohol Depend. 2019 Feb 1;195:193-197. doi: 10.1016/j.drugalcdep.2018.11.016. Epub 2019 Jan 9.
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