Schweinsberg F, Bürkle V
J Cancer Res Clin Oncol. 1985;109(3):200-2. doi: 10.1007/BF00390357.
The concurrent administration of N-nitroso-N-methylbenzylamine (NMBA) (10 mg/l drinking water) and sodium nitrite (5 g or 1 g/kg basic diet) induces enhanced progression of esophageal tumors. Pathologic changes of the respiratory system, which do not occur with administration of NMBA alone, are also observed. These findings call for re-evaluation of the toxicological significance of nitrite.
同时给予N-亚硝基-N-甲基苄胺（NMBA）（饮用水中含量为10毫克/升）和亚硝酸钠（5克或1克/千克基础饮食）会促使食管肿瘤进展加快。单独给予NMBA时未出现的呼吸系统病理变化也被观察到。这些发现要求对亚硝酸盐的毒理学意义进行重新评估。
