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超声乳化手术对假性剥脱综合征患者早期球后血流的影响。

The effect of phacoemulsification surgery on early stage retrobulbar blood flow in patients with pseudoexfoliation syndrome.

作者信息

Aydın Nihat, Tufek Melek, Kaya Ahmet Turan, Akman Burcu, Nalcacıoglu Pınar

机构信息

Department of Ophthalmology, Amasya University, Sabuncuoglu Serefeddin Training and Research Hospital, Amasya, Turkey.

Department of Radiology, Inonu University Faculty of Medicine, Malatya, Turkey.

出版信息

Int Ophthalmol. 2025 Mar 14;45(1):100. doi: 10.1007/s10792-025-03470-0.

DOI:10.1007/s10792-025-03470-0
PMID:40085286
Abstract

PURPOSE

Evaluation of the effect of phacoemulsification surgery on retrobulbar blood flow in cataract patients with pseudoexfoliation syndrome (PES).

METHODS

The 104 eyes of 52 cataract patients with bilateral PES were included in the study. The preoperative and the postoperative first month peak systolic velocity (PSV), end-diastolic velocity (EDV), resistive index (RI), and pulsatility index (PI) values of the central retinal artery (CRA) and ophthalmic artery (OA) of the eyes that underwent surgery and the other eyes that did not were evaluated with color Doppler ultrasonography. While the preoperative and postoperative 1st month values of the operated eye were compared, postoperative 1st month values of the operated eye were compared with the other eye that did not undergo surgery.

RESULTS

PSV and EDV values of the CRA and OA were found to be statistically significantly lower in the postoperative period compared to the preoperative period in the operated eye (p = 0.05, p = 0.017, p < 0.001, p = 0.003, respectively). When the operated and non-operated eyes were compared, the CRA PSV value was statistically significantly lower in the operated eye while no statistically significant change was observed between the groups in terms of the CRA EDV and OA PSV and EDV values (p = 0.043, p = 0.153, p = 0.091, p = 0.264, respectively). No difference was present between the groups in terms of RI and PI values of the CRA and OA (p > 0.05).

CONCLUSION

Phacoemulsification surgery causes a decrease in retrobulbar blood flow in the early postoperative period in cataract patients with PES.

摘要

目的

评估超声乳化手术对假性剥脱综合征(PES)白内障患者球后血流的影响。

方法

本研究纳入了52例双侧PES白内障患者的104只眼。对接受手术的眼和未接受手术的另一只眼,使用彩色多普勒超声评估术前及术后第一个月视网膜中央动脉(CRA)和眼动脉(OA)的收缩期峰值流速(PSV)、舒张末期流速(EDV)、阻力指数(RI)和搏动指数(PI)值。比较手术眼术前和术后第一个月的值,同时将手术眼术后第一个月的值与未接受手术的另一只眼进行比较。

结果

手术眼术后CRA和OA的PSV和EDV值与术前相比有统计学显著降低(分别为p = 0.05、p = 0.017、p < 0.001、p = 0.003)。比较手术眼和未手术眼时,手术眼的CRA PSV值有统计学显著降低,而CRA EDV、OA PSV和EDV值在两组之间未观察到统计学显著变化(分别为p = 0.043、p = 0.153、p = 0.091、p = 0.264)。CRA和OA的RI和PI值在两组之间无差异(p > 0.05)。

结论

超声乳化手术会导致PES白内障患者术后早期球后血流减少。

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本文引用的文献

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Pseudoexfoliation syndrome: The critical role of the extracellular matrix in pathogenesis and treatment.假性剥脱综合征:细胞外基质在发病机制和治疗中的关键作用。
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Ocular microvascular damage in autoimmune rheumatic diseases: The pathophysiological role of the immune system.自身免疫性风湿病的眼部微血管损伤:免疫系统的病理生理学作用。
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Turk J Ophthalmol. 2019 Apr 30;49(2):61-67. doi: 10.4274/tjo.galenos.2018.10734.
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Intraoperative intraocular pressure fluctuation during standard phacoemulsification in real human patients.真实人类患者在标准超声乳化白内障吸除术中的术中眼压波动。
Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 2019 Feb;163(1):75-79. doi: 10.5507/bp.2018.065. Epub 2018 Nov 6.
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Retrobulbar hemodynamics and aqueous humor levels of endothelin-1 in exfoliation syndrome and exfoliation glaucoma.剥脱综合征和剥脱性青光眼中的球后血流动力学及内皮素-1的房水水平
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The risk of ischemic optic neuropathy post phacoemulsification cataract surgery.白内障超声乳化吸除术后缺血性视神经病变的风险。
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Aqueous humor endothelin-1 and total retinal blood flow in patients with non-proliferative diabetic retinopathy.非增殖性糖尿病视网膜病变患者房水内皮素-1与视网膜总血流量
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Bromfenac ophthalmic solution 0.09% as an adjunctive therapy to topical steroids after cataract surgery in pseudoexfoliation syndrome.溴芬酸钠滴眼液 0.09%作为假性剥脱综合征白内障手术后局部皮质类固醇的辅助治疗。
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