Chou Po-Hsin, Chen Jing-Jie, Chen Chen-Sheng, Wang Shih-Tien, Liu Chien-Lin, Shih Shih-Liang
School of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan.
Department of Orthopedics and Traumatology, Taipei Veterans General Hospital, Taipei, Taiwan.
BMC Musculoskelet Disord. 2025 Mar 17;26(1):267. doi: 10.1186/s12891-025-08504-3.
OLIF (oblique lumbar interbody fusion) is a minimally invasive surgery to treat spinal instability. However, clinical studies indicated the early degeneration of adjacent segments after surgery. The rod stiffness of OLIF was associated with change at adjacent segments. Therefore, the study aimed to compare the biomechanical effects of OLIF with different rod material properties using the finite element (FE) method.
A validated L1-L5 lumbar spine was conducted in the biomechanical analysis using FE software ANSYS. The FE model of OLIF with a rod was created. Current biocompatible materials for the rod of the OLIF model were changed, including titanium alloy (OLIF_Ti), nickel-titanium alloy (OLIF_NiTi), and polycarbonate urethane (OLIF_PCU) rod. Four FE models, consisting of the intact model (INT) and implant models, were created. Hybrid control loads, such as flexion, extension, rotation, and lateral bending, were subjected to four models on the L1 vertebral body. The bottom of the L5 vertebral body was fixed.
At the surgical level, while compared to the INT model, the OLIF_Ti and OLIF_NiTi model resulted in a ROM reduction of over 40% at least, but the OLIF_PCU changed about 10% in flexion and extension. At adjacent level L2-L3, the FE results indicated that the OLIF_Ti and OLIF_NiTi model increased more stress by about 12% at least than the INT model at the adjacent segment, but it demonstrated that the OLIF_PCU would not result in stress rise at the adjacent level L2-L3 in flexion and extension.
The study concluded that rod stiffness was associated with change at the adjacent segments. The use of OLIF surgery with PCU rods can minimize the impact of the adjacent segment after lumbar fusion.
斜外侧腰椎椎间融合术(OLIF)是一种治疗脊柱不稳的微创手术。然而,临床研究表明该手术后相邻节段会早期退变。OLIF的棒刚度与相邻节段的变化有关。因此,本研究旨在使用有限元(FE)方法比较不同棒材料特性的OLIF的生物力学效应。
使用FE软件ANSYS对经过验证的L1-L5腰椎进行生物力学分析。创建了带棒的OLIF有限元模型。改变了OLIF模型棒的当前生物相容性材料,包括钛合金(OLIF_Ti)、镍钛合金(OLIF_NiTi)和聚碳酸酯聚氨酯(OLIF_PCU)棒。创建了四个有限元模型,包括完整模型(INT)和植入模型。对L1椎体上的四个模型施加混合控制载荷,如前屈、后伸、旋转和侧方弯曲。L5椎体底部固定。
在手术节段,与INT模型相比,OLIF_Ti和OLIF_NiTi模型至少使活动度降低了40%以上,但OLIF_PCU在屈伸时改变了约10%。在相邻节段L2-L3,有限元结果表明,OLIF_Ti和OLIF_NiTi模型在相邻节段的应力比INT模型至少增加了约12%,但结果表明OLIF_PCU在屈伸时不会导致相邻节段L2-L3的应力升高。
该研究得出结论,棒刚度与相邻节段的变化有关。使用PCU棒进行OLIF手术可使腰椎融合术后相邻节段的影响最小化。