Arokoyo Olorunleke M, Adeleye Collins T, Hyacinth Winifred U, Zubair Abdulahi, Omodele Abdulrahman, Agada Frank
Otolaryngology, Surgery Interest Group Africa, Lagos, NGA.
Otolaryngology, York and Scarborough Teaching Hospitals NHS Foundation Trust, York, GBR.
Cureus. 2025 Feb 13;17(2):e78931. doi: 10.7759/cureus.78931. eCollection 2025 Feb.
Reinke's oedema is a benign pathology of the vocal fold characterised by polypoidal degeneration of its subepithelial space, with resulting dysphonia and in severe cases dyspnoea. It is more common among females and smoking is a strong risk factor. Multiple conditions of the larynx ranging from benign to malignant diseases, which can also present with voice changes and dyspnoea, need to be ruled out when evaluating a patient for Reinke's oedema. The quality of evaluation can be directly influenced by the level of training and experience of the assessor and the diagnostic resources available. This can pose a challenge for the evaluation and management of Reinke's oedema in Africa, as there is a significantly low ENT surgeon-to-patient ratio within the continent, and a lot of health settings are resource-constrained. This review aimed to examine the available literature on the epidemiology, management, and outcomes of Reinke's oedema in Africa. A literature search on Reinke's oedema was conducted on PubMed, Ovid Online, and African Journal Online, from inception till date. Articles were screened for their relevance to the epidemiology, management, and outcomes of Reinke's oedema in Africa. Results were reported according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) extension for scoping reviews. No article satisfied the eligibility criteria used in this review. The dearth of literature from this scoping review could be reflective of the significantly low reach and availability of ENT services in Africa, the low percentage of females who smoke in Africa when compared to other continents, and the relatively rare nature of Reinke's oedema. Our study has established a gap in the literature and highlights a need for further research.
莱因克水肿是一种声带的良性病变,其特征为上皮下间隙呈息肉样变性,可导致发音困难,严重时可出现呼吸困难。该病在女性中更为常见,吸烟是一个重要的危险因素。在评估疑似莱因克水肿的患者时,需要排除多种从良性到恶性的喉部疾病,这些疾病也可能表现为声音改变和呼吸困难。评估的质量会直接受到评估者的培训水平和经验以及可用诊断资源的影响。这对非洲莱因克水肿的评估和管理构成了挑战,因为非洲大陆耳鼻喉科医生与患者的比例极低,而且许多医疗机构资源有限。本综述旨在研究非洲关于莱因克水肿的流行病学、管理及治疗结果的现有文献。在PubMed、Ovid Online和African Journal Online上对莱因克水肿进行了从创刊至今的文献检索。筛选与非洲莱因克水肿的流行病学、管理及治疗结果相关的文章。结果根据系统评价和Meta分析的首选报告项目(PRISMA)扩展版进行报告,用于范围综述。没有文章符合本综述使用的纳入标准。本次范围综述文献的匮乏可能反映出非洲耳鼻喉科服务的可及性和可得性极低、与其他大陆相比非洲吸烟女性的比例较低以及莱因克水肿相对罕见的性质。我们的研究揭示了文献中的空白,并强调了进一步研究的必要性。