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采用微型磨除器的瑞内氏(Reinke)水肿的嗓音外科学手术。

Phonosurgery of Reinke's edema with microdebrider.

机构信息

Department of Otorhinolaryngology, University of Catania, Via S.Sofia 14, 95125, Catania, Italy.

出版信息

Eur Arch Otorhinolaryngol. 2022 Aug;279(8):4053-4059. doi: 10.1007/s00405-022-07377-9. Epub 2022 Apr 11.

DOI:10.1007/s00405-022-07377-9
PMID:35403885
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9249694/
Abstract

PURPOSE

To present our experience with a new microsurgical approach for treatment of the Reinke's edema in suspension laryngoscopy-microdebridement. After a short review of existing literature we introduce speech therapy before and after the surgery into the protocol.

METHODS

The authors compare the phonatory outcome, laryngostroboscopical results and subjective improvement of the voice of 30 patients with Reinke's edema that were operated with either microdebridement or cold steel surgery techniques. "Sandwich" speech therapy strategy was applied for the vocal rehabilitation before and after surgery in both patient groups.

RESULTS

After the microdebridement and the speech therapy the mucosal wave was regular, symmetric and periodic in all patients. No signs of abnormal scar tissue or anterior adhesions were observed. Significant improvement of vocal parameters was found after the surgery in both groups of patients: operated with the microdebridement technique and the cold steel technique. The subjective voice evaluated by Voice Handicap Index (VHI-10) was improved for both patient groups in a homogenous way.

CONCLUSIONS

Based on the similarity of the vocal outcome in the two groups, microdebridement of the vocal folds is an excellent method for removing the edema of the Reinke's space. Careful suction at a low voltage protects the lamina propria during the microdebridement. The authors discuss the indication to this innovating procedure in patients with difficult laryngeal exposure and small operating field.

摘要

目的

介绍我们在悬雍垂喉镜-显微清创术治疗 Reinke 水肿方面的新微创手术经验。在简要回顾现有文献后,我们将术前和术后语音治疗纳入了方案。

方法

作者比较了 30 例接受显微清创术或冷钢手术治疗的 Reinke 水肿患者的发声效果、喉频闪检查结果和声音主观改善情况。在两组患者中,均采用“三明治”式语音治疗策略进行术前和术后的嗓音康复。

结果

在显微清创术和语音治疗后,所有患者的黏膜波均规则、对称且周期性。未观察到异常瘢痕组织或前粘连的迹象。两组患者手术后的嗓音参数均有显著改善:接受显微清创术和冷钢技术治疗的患者。通过嗓音障碍指数(VHI-10)评估的主观嗓音也以相同的方式得到改善。

结论

基于两组患者的发声效果相似,声带的显微清创术是去除 Reinke 间隙水肿的极佳方法。在显微清创过程中,以低电压小心抽吸可保护固有层。作者讨论了在喉暴露困难和手术视野小的患者中应用这一创新手术的适应证。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/461c/9249694/1cb48118e9b4/405_2022_7377_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/461c/9249694/0a5f9598383b/405_2022_7377_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/461c/9249694/62e5f2a79ba9/405_2022_7377_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/461c/9249694/1cb48118e9b4/405_2022_7377_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/461c/9249694/0a5f9598383b/405_2022_7377_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/461c/9249694/62e5f2a79ba9/405_2022_7377_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/461c/9249694/1cb48118e9b4/405_2022_7377_Fig3_HTML.jpg

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Exploring the Pathophysiology of Reinke's Edema: The Cellular Impact of Cigarette Smoke and Vibration.探索 Reinke 水肿的病理生理学:香烟烟雾和振动的细胞影响。
Laryngoscope. 2021 Feb;131(2):E547-E554. doi: 10.1002/lary.28855. Epub 2020 Jun 22.
2
Surgical and Nonsurgical Lines of Treatment of Reinke's Edema: A Systematic Literature Review.声带间隙水肿的手术与非手术治疗方法:一项系统文献综述
J Voice. 2021 May;35(3):502.e1-502.e11. doi: 10.1016/j.jvoice.2019.10.016. Epub 2019 Nov 21.
3
Two-handed tying technique in vocal fold mucosa microsuture for the treatment of Reinke's edema.
双手打结技术在声带黏膜微小缝合治疗瑞氏水肿中的应用。
Eur Arch Otorhinolaryngol. 2019 Jul;276(7):2015-2022. doi: 10.1007/s00405-019-05480-y. Epub 2019 May 23.
4
Proteomic Analysis of Vocal Fold Fibroblasts Exposed to Cigarette Smoke Extract: Exploring the Pathophysiology of Reinke's Edema.声韧带成纤维细胞暴露于香烟烟雾提取物的蛋白质组学分析:探索任克氏水肿的病理生理学。
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Reinke's Edema.赖内克水肿
Otolaryngol Clin North Am. 2019 Aug;52(4):627-635. doi: 10.1016/j.otc.2019.03.006. Epub 2019 May 14.
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