赖克氏水肿的临床病理研究。
A Clinico-pathological study of Reinke'S oedema.
作者信息
Goswami Saileswar, Patra Tarun Kumar
机构信息
Department of E.N.T, N. R. S. Medical College, 700008 Kolkata.
出版信息
Indian J Otolaryngol Head Neck Surg. 2003 Jul;55(3):160-5. doi: 10.1007/BF02991943.
An analysis of 92 eases of Reinke's oedema was done in this study. It wen most often seen in middle-aged persons. A Male predilection (57%) was found. In 68 (74%) cases, the lesions were unilateral and in 24 (26%) teses, the lesions were bilateral. Smoking (83%), vocal alms or misuse (80%) and chromnic respiratory tract infection (43%) were the main aetiological factors. No significant relationship of reinke's oedema with hypotkyroidsm was found. There were no dysplastic changes in the epithelium The treatment of reinke's oedema is a combination of surgery and vocal rehabilitation. Conventional microlaryngeal surgery is ideal for the treatment of Reinke's oedema. Acquired laryngeal web involving the anterior part of the vocal cords may develop if stripping of the both vocal cords is performed carelessly. Operating measures do not prevent recurrences of Reinke's oedema. Voice therapy and cessation of smoking in the postoperative period play important roles in the long term treatment results of Reinke's oedema.
本研究对92例任克氏水肿病例进行了分析。该病多见于中年人，男性居多（占57%）。68例（74%）病变为单侧，24例（26%）为双侧。吸烟（83%）、发声习惯或用嗓不当（80%）以及慢性呼吸道感染（43%）是主要病因。未发现任克氏水肿与甲状腺功能减退有显著关联。上皮无发育异常改变。任克氏水肿的治疗是手术与嗓音康复相结合。传统的显微喉镜手术是治疗任克氏水肿的理想方法。若双侧声带剥离操作不慎，可能会形成累及声带前部的后天性喉蹼。手术措施无法防止任克氏水肿复发。术后的嗓音治疗和戒烟对任克氏水肿的长期治疗效果起着重要作用。
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