Zhang Xinyue, Li Dongyang, Du Yanwei
College of Integrated Traditional Chinese and Western Medicine, Changchun University of Chinese Medicine Changchun 130117, Jilin, China.
School of Nursing, Jilin University Changchun 130021, Jilin, China.
Am J Transl Res. 2025 Feb 15;17(2):1170-1177. doi: 10.62347/KVCV7377. eCollection 2025.
The neutrophil to lymphocyte ratio (NLR) is a simple, reliable, and easily accessible composite index that has garnered increasing attention in cardiovascular research. NLR is closely associated with the onset, progression, and prognosis of various cardiovascular diseases. This article reviews the etiological and prognostic roles of NLR in cardiovascular conditions such as coronary atherosclerotic heart disease, hypertension, arrhythmia, heart failure, and valvular heart disease. Studies have shown that NLR is involved in the pathophysiologic processes of these diseases and holds significant predictive value for their prognosis. Additionally, compared to other inflammatory markers, NLR offers advantages such as low cost, repeatability, and the ability to be measured at the community-level primary healthcare settings, thus providing new insight for prognostic prediction in conditions like coronary artery disease, arrhythmia, hypertension, heart failure, and valvular heart disease.
中性粒细胞与淋巴细胞比值（NLR）是一个简单、可靠且易于获取的综合指标，在心血管研究中受到越来越多的关注。NLR与各种心血管疾病的发生、发展及预后密切相关。本文综述了NLR在冠心病、高血压、心律失常、心力衰竭和心脏瓣膜病等心血管疾病中的病因及预后作用。研究表明，NLR参与了这些疾病的病理生理过程，对其预后具有重要的预测价值。此外，与其他炎症标志物相比，NLR具有成本低、可重复性强以及能够在社区基层医疗环境中进行检测等优势，从而为冠心病、心律失常、高血压、心力衰竭和心脏瓣膜病等疾病的预后预测提供了新的视角。
