Soysal Pinar, Smith Lee
Faculty of Medicine, Department of Geriatric Medicine, Bezmialem Vakif University, 34093, Fatih, Istanbul, Turkey.
Department of Geriatric Medicine, Faculty of Medicine, Bezmialem Vakif University, Adnan Menderes Bulvarı Vatan Street, 34093, Fatih, Istanbul, Turkey.
Aging Clin Exp Res. 2024 Mar 13;36(1):66. doi: 10.1007/s40520-024-02724-8.
This study aims to compare frequency and coexistence of geriatric syndromes in older patients with dementia to those without dementia.
1392 patients admitted to geriatric outpatient clinics were evaluated. Evaluations for eleven geriatric syndromes including polypharmacy, malnutrition, fraility, sarcopenia, dysphagia, urinary incontinence, fear of falling, falls, insomnia, excessive daytime sleepiness, and orthostatic hypotension (OH) were carried out in consultation with the patient and the caregiver. Two groups with and without dementia were matched according to age and gender using the propensity score matching method.
A total of 738 patients, 369 with dementia and 369 without dementia were included, of whom 70.1% were female and the mean age was 80.5 ± 6.8. Polypharmacy, malnutrition, frailty, sarcopenia, dysphagia, fear of falling, and excessive daytime sleepiness were significantly higher in patients with dementia (p < 0.05). There was no difference between OH, urinary incontinence and insomnia between groups (p > 0.05). The co-existence of 0, 1, 2, 3, 4 and ≥ 5 geriatric syndromes in the same patient was 4.3%, 10.2%, 11.8%, 16.8%, 13.4% and 43.7% in non-dementia patients, respectively; 2.4%, 7.2%, 9.6%, 8.3%, 10.4% and 62.1% in those with dementia, respectively (p < 0.05).
The presence and co-existence of geriatric syndromes is common in patients with dementia. These geriatric syndromes should be examined by clinicians and healthcare professionals who work with the demented population, so that more successful management of dementia patients may be achieved.
本研究旨在比较老年痴呆患者与非痴呆老年患者中老年综合征的发生率及共存情况。
对1392名老年门诊患者进行评估。通过与患者及其照料者沟通,对包括多重用药、营养不良、衰弱、肌肉减少症、吞咽困难、尿失禁、跌倒恐惧、跌倒、失眠、日间过度嗜睡和体位性低血压(OH)在内的11种老年综合征进行评估。采用倾向得分匹配法,根据年龄和性别对痴呆组和非痴呆组进行匹配。
共纳入738例患者,其中369例患有痴呆,369例未患痴呆,女性占70.1%,平均年龄为80.5±6.8岁。痴呆患者的多重用药、营养不良、衰弱、肌肉减少症、吞咽困难、跌倒恐惧和日间过度嗜睡发生率显著更高(p<0.05)。两组间OH、尿失禁和失眠发生率无差异(p>0.05)。非痴呆患者中,同一患者并存0、1、2、3、4及≥5种老年综合征的比例分别为4.3%、10.2%、11.8%、16.8%、13.4%和43.7%;痴呆患者中分别为2.4%、7.2%、9.6%、8.3%、10.4%和62.1%(p<0.05)。
老年综合征在痴呆患者中普遍存在且常并存。临床医生和从事痴呆患者护理工作的医护人员应检查这些老年综合征,以便更成功地管理痴呆患者。