Udhayakumari Duraisamy
Department of Chemistry, Rajalakshmi Engineering College, Chennai, 602105, India.
J Fluoresc. 2025 Mar 17. doi: 10.1007/s10895-025-04253-7.
The detection of copper ions (Cu⁺) through colorimetric and fluorometric methods has garnered significant attention due to the biological, environmental, and medical importance of Cu⁺. These detection techniques have proven to be highly effective due to their simplicity, cost-efficiency, high sensitivity, and suitability for bioimaging applications. This critical review begins by briefly addressing the sources, applications, and toxicity of copper ion sensors. It then provides an in-depth classification of fluorescent and colorimetric Cu⁺ sensors based on their receptors, organizing them into various categories such as anthracene, pyridine, pyrazole, pyrrole, naphthalene, imidazole, and quinoline functionalized sensing systems, with a focus on developments since 2016.
由于铜离子（Cu⁺）在生物学、环境和医学方面的重要性，通过比色法和荧光法检测铜离子已引起了广泛关注。这些检测技术因其简单性、成本效益、高灵敏度以及适用于生物成像应用而被证明是非常有效的。这篇批判性综述首先简要介绍了铜离子传感器的来源、应用和毒性。然后根据其受体对荧光和比色Cu⁺传感器进行了深入分类，将它们分为蒽、吡啶、吡唑、吡咯、萘、咪唑和喹啉功能化传感系统等各类，重点关注2016年以来的进展。
