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[德国的疫苗接种提醒:以人乳头瘤病毒疫苗接种为例对未来的盘点与构想:InveSt人乳头瘤病毒项目结果报告]

[Vaccination reminders in Germany: inventory and ideas for tomorrow using the example of HPV vaccination : Report on the results of the InveSt HPV project].

作者信息

Takla Anja, Wulkotte Elisa, Bichel Yvonne, Lachmann Johannes, Trübswetter Angelika, Wilhelm Julia, Zettel Annabel, Schmid-Küpke Nora

机构信息

Fachgebiet Impfprävention, STIKO, Abteilung für Infektionsepidemiologie, Robert Koch-Institut, Berlin, Deutschland.

Robert Koch-Institut, Seestr. 10, 13353, Berlin, Deutschland.

出版信息

Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz. 2025 Apr;68(4):398-407. doi: 10.1007/s00103-025-04030-8. Epub 2025 Mar 17.

DOI:10.1007/s00103-025-04030-8
PMID:40097665
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11950045/
Abstract

In Germany, vaccinations take place almost exclusively in physicians' private practices. This means that every contact with a practice or physician is an important opportunity to receive a recommended vaccination. The effectiveness of invitation and reminder systems for the implementation of recommended vaccinations has already been proven by studies, but in contrast to many other countries, such systems are not used across the board in Germany. The "Intervention Study to Increase HPV Vaccination Coverage in Germany" (InveSt HPV) therefore addresses, among other things, the question of what barriers exist to the use and dissemination of invitation and vaccination reminder systems. To this end, two nationwide quantitative surveys of (i) 345 pediatricians in private practices and (ii) 1805 parents with children aged 9 to 14 as well as a survey of 46 statutory health insurances with around 51 million insured persons were conducted. The survey results and other evidence compiled by the project team formed the basis for a workshop with vaccination-relevant stakeholders from the healthcare sector. The aim of the workshop was to work together on concepts for a future invitation and vaccination reminder system in Germany using the specific example of the HPV (Human Papillomavirus) vaccination. This report presents the core results of the surveys conducted and selected additional evidence compiled by the project team for the workshop. Finally, the workshop and the key elements developed by the participants for an HPV-related invitation and vaccination reminder system 2.0 are described.

摘要

在德国,疫苗接种几乎完全在医生的私人诊所进行。这意味着与诊所或医生的每次接触都是接受推荐疫苗接种的重要机会。邀请和提醒系统在实施推荐疫苗接种方面的有效性已得到研究证实,但与许多其他国家不同的是,此类系统在德国并未得到广泛应用。因此,“提高德国HPV疫苗接种覆盖率干预研究”(InveSt HPV)除其他事项外,还探讨了邀请和疫苗接种提醒系统的使用和推广存在哪些障碍的问题。为此,对(i)345名私人诊所的儿科医生和(ii)1805名有9至14岁子女的父母进行了两项全国性定量调查,并对46家法定健康保险公司的约5100万名被保险人进行了调查。调查结果以及项目团队汇编的其他证据为与医疗保健部门与疫苗接种相关的利益相关者举办的研讨会奠定了基础。该研讨会的目的是利用HPV(人乳头瘤病毒)疫苗接种的具体例子,共同探讨德国未来邀请和疫苗接种提醒系统的概念。本报告介绍了所进行调查的核心结果以及项目团队为研讨会汇编的其他选定证据。最后,描述了研讨会以及参与者为HPV相关邀请和疫苗接种提醒系统2.0制定的关键要素。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/83f9/11950045/91b72e64be9e/103_2025_4030_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/83f9/11950045/97673578f6fb/103_2025_4030_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/83f9/11950045/8446b2721660/103_2025_4030_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/83f9/11950045/53e66c48647b/103_2025_4030_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/83f9/11950045/91b72e64be9e/103_2025_4030_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/83f9/11950045/97673578f6fb/103_2025_4030_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/83f9/11950045/8446b2721660/103_2025_4030_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/83f9/11950045/53e66c48647b/103_2025_4030_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/83f9/11950045/91b72e64be9e/103_2025_4030_Fig4_HTML.jpg

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本文引用的文献

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NPJ Vaccines. 2023 Oct 31;8(1):167. doi: 10.1038/s41541-023-00771-2.
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Systematic review and meta-analysis comparing educational and reminder digital interventions for promoting HPV vaccination uptake.比较教育和提醒数字干预措施以促进人乳头瘤病毒(HPV)疫苗接种率的系统评价和荟萃分析。
NPJ Digit Med. 2023 Aug 29;6(1):162. doi: 10.1038/s41746-023-00912-w.
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Digital Health Interventions to Improve Adolescent HPV Vaccination: A Systematic Review.
改善青少年人乳头瘤病毒疫苗接种的数字健康干预措施:一项系统评价
Vaccines (Basel). 2023 Jan 22;11(2):249. doi: 10.3390/vaccines11020249.
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Human papillomavirus vaccination coverage, policies, and practical implementation across Europe.欧洲的人乳头瘤病毒疫苗接种覆盖率、政策和实际实施情况。
Vaccine. 2020 Feb 5;38(6):1315-1331. doi: 10.1016/j.vaccine.2019.11.081. Epub 2019 Dec 10.
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