Nagy Hosam, Saleh Wafaa, Kannishy Ghada El, Youssef Jilan Mohamed
Oral Medicine, Periodontology, Diagnosis and Oral Radiology Department, Faculty of Dentistry, Mansoura University, Mansoura City, 33516, Egypt.
Internal Medicine Department, Faculty of Medicine, Mansoura University, Mansoura, Egypt.
Odontology. 2025 Mar 17. doi: 10.1007/s10266-025-01071-y.
The current study aims to investigate the oral health of end-stage renal diseases (ESRD) patients undergoing hemodialysis and to correlate it with the biochemical profile of the patients. The current study included 43 ESRD patients on regular hemodialysis. The oral hygiene status, dental, and periodontal health were measured by the following indices: decayed, missed, and filled teeth (DMFT) index, visible plaque index (VPI), and Russell periodontal index (RPI). Several biochemical, hormonal, and hematological parameters were evaluated for each patient. The correlation of the oral health status with the biochemical profile of the patients was measured. The mean age of the participants in the current study was (51.67 ± 14.7) years. About 81% of the participants were hypertensive (35), 19% were diabetic (8), and 28% showed HCV positivity (12). VPI showed 30% of patients had fair oral hygiene and 44% had poor oral hygiene. According to RPI, periodontitis was detected in more than 95% of patients. It was significantly correlated with the age and body mass index (BMI) of the patients. DMFT index was significantly positively correlated to RPI and serum transferrin saturation. RPI scores showed a significant correlation between the ages of the patients and their BMI. VPI significantly correlated with serum calcium, but not with other biochemical variables. ESRD patients treated with hemodialysis showed several oral health concerns. Most of these patients had periodontitis, which was more frequent in diabetics and elderly patients. Advanced grades of periodontitis were associated with older age and increased BMI.
本研究旨在调查接受血液透析的终末期肾病（ESRD）患者的口腔健康状况，并将其与患者的生化指标相关联。本研究纳入了43例接受定期血液透析的ESRD患者。通过以下指标测量口腔卫生状况、牙齿和牙周健康：龋失补牙（DMFT）指数、可见菌斑指数（VPI）和罗素牙周指数（RPI）。对每位患者评估了多项生化、激素和血液学参数。测量了口腔健康状况与患者生化指标之间的相关性。本研究参与者的平均年龄为（51.67±14.7）岁。约81%的参与者患有高血压（35例），19%患有糖尿病（8例），28%呈丙型肝炎病毒阳性（12例）。VPI显示30%的患者口腔卫生良好，44%的患者口腔卫生较差。根据RPI，超过95%的患者检测出牙周炎。它与患者的年龄和体重指数（BMI）显著相关。DMFT指数与RPI和血清转铁蛋白饱和度显著正相关。RPI评分显示患者年龄与BMI之间存在显著相关性。VPI与血清钙显著相关，但与其他生化变量无关。接受血液透析治疗的ESRD患者存在多种口腔健康问题。这些患者大多患有牙周炎，在糖尿病患者和老年患者中更为常见。晚期牙周炎与年龄较大和BMI增加有关。
