Elhusseiny Ghada A, Saleh Wafaa
Oral Medicine, Periodontology, Diagnosis and Oral Radiology Department, Faculty of Dentistry, Mansoura University, Mansoura, Egypt.
Clin Med Insights Pediatr. 2024 Aug 27;18:11795565241271689. doi: 10.1177/11795565241271689. eCollection 2024.
Chronic kidney disease (CKD) in children presents multifaceted challenges, impacting various aspects of health, including oral health. This narrative review provides a comprehensive synthesis of literature focusing on the oral health status of pediatric CKD patients, encompassing oral manifestations, dental considerations, and management challenges associated with hemodialysis and kidney transplantation. A comprehensive search strategy was employed, utilizing databases such as PubMed, Scopus, Web of Science, and Google Scholar, to identify relevant literature on oral manifestations in children with CKD, including those undergoing hemodialysis or renal transplantation. Search terms were carefully selected to capture studies examining enamel hypoplasia, dental caries, delayed tooth eruption, gingival diseases, periodontal diseases, radiographic alterations, craniofacial development, dry mouth, and changes in the oral mucosa. Our narrative review meticulously selected articles through a systematic process. Ultimately, 12 studies meeting the inclusion criteria were included in the review. Relevant data from each included study were independently extracted and synthesized, focusing on oral manifestations and their implications in pediatric CKD patients. The synthesized findings were organized and presented in a structured manner within the review article, considering their clinical implications and informing recommendations for dental management of children with CKD. This article highlights the importance of a coordinated effort between nephrologists, dentists, and other healthcare professionals in providing holistic care for pediatric CKD patients. A comprehensive understanding of the oral health status of these children, along with proactive dental management strategies, contributes to improved overall health outcomes and a better quality of life. This review aims to serve as a valuable resource for the oral healthcare providers involved in the care of pediatric CKD patients.
儿童慢性肾脏病（CKD）带来多方面挑战，影响包括口腔健康在内的各个健康领域。本叙述性综述全面综合了文献，聚焦于儿科CKD患者的口腔健康状况，涵盖口腔表现、牙科考量以及与血液透析和肾移植相关的管理挑战。采用了全面的检索策略，利用如PubMed、Scopus、科学网和谷歌学术等数据库，以识别有关CKD儿童口腔表现的相关文献，包括那些接受血液透析或肾移植的儿童。仔细选择检索词以捕捉研究牙釉质发育不全、龋齿、牙齿萌出延迟、牙龈疾病、牙周疾病、影像学改变、颅面发育、口干和口腔黏膜变化的研究。我们的叙述性综述通过系统流程精心挑选文章。最终，12项符合纳入标准的研究被纳入综述。对每项纳入研究的相关数据进行独立提取和综合，重点关注口腔表现及其对儿科CKD患者的影响。在综述文章中，综合研究结果以结构化方式进行组织和呈现，考虑其临床意义并为CKD儿童的牙科管理提供建议。本文强调了肾病学家、牙医和其他医疗保健专业人员之间协调努力为儿科CKD患者提供全面护理的重要性。对这些儿童口腔健康状况的全面了解以及积极的牙科管理策略有助于改善整体健康结果和提高生活质量。本综述旨在为参与儿科CKD患者护理的口腔医疗服务提供者提供有价值的资源。
