慢性肾脏病患者口腔感染的患病率：一项横断面研究。

Prevalence of oral infections in chronic kidney disease patients: A cross-sectional study.

机构信息

Hospital Geral de Santo António, Oporto, Portugal.

Department of Odontostomatology, Faculty of Medicine and Health Sciences (School of Dentistry), University of Barcelona, Barcelona, Spain.

出版信息

Oral Dis. 2024 May;30(4):2708-2715. doi: 10.1111/odi.14663. Epub 2023 Jul 1.

DOI:10.1111/odi.14663

PMID:37392430

Abstract

OBJECTIVES

The purpose of this investigation was to analyze the prevalence of apical periodontitis (AP) and periodontal disease (periodontitis) (PD) in Chronic kidney disease (CKD) patients in relation to their treatment phase.

SUBJECTS AND METHODS

In this cross-sectional study, 188 patients with CKD were divided into two groups: patients without dialysis (WD group, n = 53) and patients on dialysis (DP group, n = 135). Panoramic radiographs were used to diagnose AP. The presence of periodontal disease was evaluated radiographically assessing alveolar bone loss. Student's t-test, chi-squared test, and logistic regression analysis were used to determine the significance of differences between groups.

RESULTS

In the WD group, 55% of patients had at least one tooth with AP, whereas in the DP group 67% had at least one tooth with AP (OR = 2.11; 95% CI = 1.09-4.08; p < 0.05). PD was more prevalent in the DP group (78%) than in the WD group (36%) (OR = 6.26; CI 95% = 3.13-12.52; p < 0.01).

CONCLUSIONS

Oral infections are more prevalent in the advanced stages of CKD. The treatment of PD and AP should be incorporated in the treatment planning of patients with CKD.

摘要

目的

本研究旨在分析与治疗阶段相关的慢性肾脏病（CKD）患者根尖周病（AP）和牙周病（PD）的患病率。

受试者和方法

在这项横断面研究中，将 188 名 CKD 患者分为两组：未透析患者（WD 组，n=53）和透析患者（DP 组，n=135）。全景片用于诊断 AP。通过评估牙槽骨丧失来评估牙周病的存在。使用学生 t 检验、卡方检验和逻辑回归分析来确定组间差异的显著性。

结果

在 WD 组中，55%的患者至少有一颗牙齿患有 AP，而在 DP 组中，67%的患者至少有一颗牙齿患有 AP（OR=2.11；95%CI=1.09-4.08；p<0.05）。PD 在 DP 组（78%）比 WD 组（36%）更为普遍（OR=6.26；95%CI 3.13-12.52；p<0.01）。