Cheng Siqi, Qin Jiafan, Hou Chengbei, Wu Yue, Du Xinyan, Liu Hongjun, Lei Shaoyuan, Li Rui, Yue Xiaolin, Guo Yansu
Beijing Geriatric Healthcare and Disease Prevention Center, Xuanwu Hospital, Capital Medical University, Beijing, China.
Evidence-Based Medicine Center, Xuanwu Hospital, Capital Medical University, Beijing, China.
J Am Med Dir Assoc. 2025 May;26(5):105550. doi: 10.1016/j.jamda.2025.105550. Epub 2025 Mar 27.
To develop the crosswalk between the Montreal Cognitive Assessment-Basic (MoCA-B) and Mini-Mental Status Examination (MMSE) based on a community-dwelling older population to facilitate data synthesis and comparison.
A cross-sectional study.
We used baseline data of 2170 subjects with total MoCA-B and MMSE scores from an ongoing prospective cohort study, the Beijing Longitudinal Disability Survey in Community Elderly (BLINDSCE).
The MoCA-B and MMSE were administered by trained assessors. Equipercentile equating was used to develop the conversion table between MoCA-B and MMSE scores in the total sample and subgroups by age, sex, residency, and education level. The mean absolute error (MAE), intraclass correlation coefficient (ICC), and Bland-Altman plot were used to evaluate the linking performance.
MoCA-B and MMSE scores converted bi-directionally for the overall sample and subgroups, with small standardized MAE (SMAE) and high ICC. The linking results between MoCA-B and MMSE scores were consistent across the total sample and the age and sex subgroups, while a 2-score difference was observed within the residency and education subgroups.
This study provides easy-to-use crosswalks between measures of MoCA-B and MMSE with precision among community-dwelling older adults. Our results help to compare and pool data across studies using either of the 2 cognitive screening tests and provide a useful reference to clinicians for better evidence-based practice in patients evaluated using different cognitive tests.
基于社区老年人群开发蒙特利尔认知评估基础版(MoCA-B)与简易精神状态检查表(MMSE)之间的转换关系,以促进数据综合分析与比较。
横断面研究。
我们使用了来自一项正在进行的前瞻性队列研究——北京社区老年人纵向残疾调查(BLINDSCE)的2170名受试者的MoCA-B和MMSE总分的基线数据。
由经过培训的评估人员进行MoCA-B和MMSE测试。采用等百分位等值法制定总样本以及按年龄、性别、居住情况和教育水平划分的亚组中MoCA-B与MMSE分数之间的转换表。使用平均绝对误差(MAE)、组内相关系数(ICC)和布兰德-奥特曼图来评估转换效果。
MoCA-B和MMSE分数在总样本和亚组中均可双向转换,标准化平均绝对误差(SMAE)较小且ICC较高。MoCA-B与MMSE分数之间的转换结果在总样本以及年龄和性别亚组中保持一致,而在居住情况和教育亚组中观察到2分的差异。
本研究提供了MoCA-B与MMSE测量指标之间易于使用的转换关系,在社区老年人群中具有较高的准确性。我们的结果有助于比较和汇总使用这两种认知筛查测试之一的各项研究的数据,并为临床医生在使用不同认知测试评估患者时更好地开展循证实践提供有用的参考。