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衰弱指数作为腹腔镜袖状胃切除术患者手术安全性和疗效的预测指标

Frailty Index as a Predictor of Operative Safety and Efficacy in Patients Undergoing Laparoscopic Sleeve Gastrectomy.

作者信息

Bekhor Eliahu Yonathan, Kirshtein Boris, Peleg Noam, Tibi Nayyera, Shmilovich Hila, Cooper Lisa, Tatarov Alex, Issa Nidal

机构信息

Rabin Medical Center, Petah Tikva, Israel.

Tel Aviv University, Tel Aviv, Israel.

出版信息

Obes Surg. 2025 May;35(5):1603-1610. doi: 10.1007/s11695-025-07713-y. Epub 2025 Mar 18.

Abstract

BACKGROUND

Bariatric surgery is an effective treatment for obesity and its associated comorbidities. However, the safety and efficacy of laparoscopic sleeve gastrectomy (LSG) for elderly and frail populations remain uncertain.

OBJECTIVES

To validate the efficacy and safety of LSG for elderly and frail patients and to assess its impact on overweight and obesity-related comorbidities.

METHODS

A retrospective cohort study of patients undergoing LSG at a university-affiliated single center between 2009 and 2022 from a prospectively maintained database. Patients were categorized into two cohorts based on age and frailty index: elderly vs younger patients and frail vs non-frail groups. Preoperative, perioperative, and postoperative data were analyzed.

RESULTS

Frailty was associated with statistically significantly higher perioperative complications (%, Clavien-Dindo of III/IV, 8 vs 3) and lower treatment success rates (% Excess Body Weight Loss, six-month, year, and two-year, 58 vs 64, 73 vs 82, 72 vs 81, and 63 vs 76, respectively). Age was not shown to alter the safety or efficacy of the operation.

CONCLUSION

While LSG is a viable option for elderly and frail patients, frailty is a significant predictor of treatment outcomes. A comprehensive assessment of individual factors, including frailty status, is essential for informed decision-making before surgery.

摘要

背景

减肥手术是治疗肥胖及其相关合并症的有效方法。然而,腹腔镜袖状胃切除术(LSG)在老年和体弱人群中的安全性和有效性仍不确定。

目的

验证LSG对老年和体弱患者的有效性和安全性,并评估其对超重和肥胖相关合并症的影响。

方法

对2009年至2022年期间在一所大学附属单中心接受LSG手术的患者进行回顾性队列研究,数据来自一个前瞻性维护的数据库。根据年龄和虚弱指数将患者分为两个队列:老年患者与年轻患者,体弱患者与非体弱患者。分析术前、围手术期和术后数据。

结果

虚弱与围手术期并发症在统计学上显著更高相关(%,Clavien-Dindo III/IV级,分别为8%和3%),治疗成功率更低(%,多余体重减轻,六个月、一年和两年,分别为58%对64%、73%对82%、72%对81%以及63%对76%)。年龄并未显示会改变手术的安全性或有效性。

结论

虽然LSG对老年和体弱患者是一种可行的选择,但虚弱是治疗结果的一个重要预测因素。在手术前,对包括虚弱状态在内的个体因素进行全面评估对于做出明智决策至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8161/12065677/8d3e81221fd1/11695_2025_7713_Fig1_HTML.jpg

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