Banner-University Medical Centre, University of Arizona, Department of Surgery, Tucson, Arizona.
Banner-University Medical Centre, University of Arizona, Department of Surgery, Tucson, Arizona.
Surg Obes Relat Dis. 2019 Sep;15(9):1582-1588. doi: 10.1016/j.soard.2019.06.028. Epub 2019 Jun 29.
The prognostic value of frailty in the elderly surgical population has been well studied across surgical specialties. However, no studies have yet explored the effects of frailty across the full spectrum of adverse events after bariatric surgery.
To study the impact of index-frailty on the full range of adverse short-term outcomes after bariatric surgery.
Metabolic and Bariatric Surgery Accreditation and Quality Improvement Program data file for 2016 was used. Descriptive analyses, univariable, and multivariable regression models, assessed for discriminative and predictive capacities, were used to assess the effects of frailty on Clavien-Dindo categorized adverse outcomes within 30 days of bariatric surgery. Frailty index was modified from Canadian Study of Health and Aging Frailty Index.
Data pooled from American Society for Bariatric Surgery-accredited bariatric surgery centers, United States.
A total of 21,426 patients aged ≥60 undergoing primary bariatric procedures were included. The prevalence of frailty as defined by the modified frailty index was 44.4%. Frail status was independently associated with higher odds of 30-day adverse events (Clavien-Dindo grades I, II, III, IV, and V). Frailty scores had weakly positive correlations with increasing age and increasing body mass index in the bariatric patients.
Frailty can be used as a risk stratification modality for patients before bariatric surgery. Further research should focus on exploring the relationship between obesity and frailty and the effects of weight loss on frailty status of bariatric patients.
衰弱在老年外科人群中的预后价值已在多个外科专业中得到充分研究。然而,尚无研究探讨衰弱对减重手术后全谱不良事件的影响。
研究指数衰弱对减重手术后短期不良结局的全面影响。
使用代谢和减重手术认证和质量改进计划 2016 年数据文件。描述性分析、单变量和多变量回归模型用于评估衰弱对术后 30 天内按 Clavien-Dindo 分类的不良结局的影响。衰弱指数由加拿大健康与衰老衰弱指数修改而来。
来自美国减重外科学会认证的减重手术中心的数据汇总,美国。
共纳入 21426 名年龄≥60 岁接受原发性减重手术的患者。根据改良衰弱指数定义,衰弱的患病率为 44.4%。衰弱状态与 30 天不良事件(Clavien-Dindo 分级 I、II、III、IV 和 V)的发生几率更高独立相关。在减重患者中,衰弱评分与年龄增加和体重指数增加呈弱正相关。
衰弱可作为减重手术前患者的风险分层手段。进一步的研究应侧重于探索肥胖与衰弱之间的关系以及减重对减重患者衰弱状态的影响。