Bernard Nathan, Sagawa Yoshimasa, Bier Nathalie, Lihoreau Thomas, Pazart Lionel, Tannou Thomas
Inserm CIC 1431, CHU Besançon, Besançon, F-25000, France.
Laboratoires de Neurosciences intégratives et clinique, unité de recherche EA 481, Université Marie et Louis Pasteur, INSERM, UMR 1322 LINC, Besançon, F-25000, France.
BMC Med Res Methodol. 2025 Mar 18;25(1):75. doi: 10.1186/s12874-025-02528-y.
BACKGROUND: Artificial intelligence (AI) tools are increasingly being used to assist researchers with various research tasks, particularly in the systematic review process. Elicit is one such tool that can generate a summary of the question asked, setting it apart from other AI tools. The aim of this study is to determine whether AI-assisted research using Elicit adds value to the systematic review process compared to traditional screening methods. METHODS: We compare the results from an umbrella review conducted independently of AI with the results of the AI-based searching using the same criteria. Elicit contribution was assessed based on three criteria: repeatability, reliability and accuracy. For repeatability the search process was repeated three times on Elicit (trial 1, trial 2, trial 3). For accuracy, articles obtained with Elicit were reviewed using the same inclusion criteria as the umbrella review. Reliability was assessed by comparing the number of publications with those without AI-based searches. RESULTS: The repeatability test found 246,169 results and 172 results for the trials 1, 2, and 3 respectively. Concerning accuracy, 6 articles were included at the conclusion of the selection process. Regarding, revealed 3 common articles, 3 exclusively identified by Elicit and 17 exclusively identified by the AI-independent umbrella review search. CONCLUSION: Our findings suggest that AI research assistants, like Elicit, can serve as valuable complementary tools for researchers when designing or writing systematic reviews. However, AI tools have several limitations and should be used with caution. When using AI tools, certain principles must be followed to maintain methodological rigour and integrity. Improving the performance of AI tools such as Elicit and contributing to the development of guidelines for their use during the systematic review process will enhance their effectiveness.
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