Taliercio C P, Olney B A, Lie J T
Mayo Clin Proc. 1985 Jul;60(7):463-8. doi: 10.1016/s0025-6196(12)60870-2.
Hypersensitivity myocarditis is an inflammatory disease of the myocardium usually related to a drug allergy. The clinical manifestations may be nonspecific, and the diagnosis is seldom suspected or established during life. We report a case that demonstrates both typical and atypical features of this disease and review the clinicopathologic correlations. This case illustrates the potential occurrence of both electrical conduction block and ventricular tachyarrhythmias, either of which may account for the mechanism of sudden death in these patients. When cardiac symptoms or electrocardiographic abnormalities (or both) occur in a setting consistent with drug allergy, hypersensitivity myocarditis should be considered. Treatment consists of discontinuation of use of the drug responsible for the reaction and, possibly, administration of corticosteroids and immunosuppressive therapy.
超敏性心肌炎是一种通常与药物过敏相关的心肌炎性疾病。其临床表现可能不具有特异性，生前很少被怀疑或确诊。我们报告一例展现了该病典型和非典型特征的病例，并回顾临床病理相关性。该病例说明了电传导阻滞和室性快速性心律失常都有可能发生，其中任何一种都可能是这些患者猝死的机制。当在与药物过敏相符的情况下出现心脏症状或心电图异常（或两者皆有）时，应考虑超敏性心肌炎。治疗包括停用引起反应的药物，可能还需给予皮质类固醇和免疫抑制治疗。
