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医疗保健和功能性食品中的微藻:β-葡聚糖的应用、药物递送创新与合成生物学

Microalgae in health care and functional foods: β-glucan applications, innovations in drug delivery and synthetic biology.

作者信息

Li Chao, Du Ming, Han Yujie, Sun Wentao, Chen Zixi, Liu Qiong, Zhu Hui, Zhao Liqing, Li Shuangfei, Wang Jiangxin

机构信息

College of Physics and Optoelectronic Engineering, Shenzhen University, Shenzhen, China.

School of Life Sciences and Food Engineering, Hanshan Normal University, Chaozhou, Guangdong, China.

出版信息

Front Pharmacol. 2025 Mar 4;16:1557298. doi: 10.3389/fphar.2025.1557298. eCollection 2025.

Abstract

Microalgae are emerging as a key player in healthcare, functional foods, and sustainable biotech due to their capacity to produce bioactive compounds like β-glucans, omega-3 fatty acids, and antioxidants in an eco-friendly manner. This review comprehensively discusses the role of microalgae in healthcare and functional foods, focusing particularly on β-glucan therapeutics, drug delivery innovations, and synthetic biology applications. In healthcare, microalgae-derived compounds show immense promise for treating diseases, boosting immunity, and tackling oxidative stress. -derived paramylon, a type of β-glucan, has shown potential in various medical applications, including immunomodulation and anticancer therapy. Synthetic biology and bioprocess engineering are enhancing microalgae's therapeutic and nutritional value, with applications in drug delivery and personalized medicine. To maximize the potential of microalgae, further research and development are needed to address scalability, regulatory alignment, and consumer acceptance, with a focus on interdisciplinary collaboration and sustainable practices to align healthcare innovation with environmental conservation.

摘要

微藻正成为医疗保健、功能性食品和可持续生物技术领域的关键角色,因为它们有能力以环保方式生产生物活性化合物,如β-葡聚糖、omega-3脂肪酸和抗氧化剂。本综述全面讨论了微藻在医疗保健和功能性食品中的作用,特别关注β-葡聚糖疗法、药物递送创新和合成生物学应用。在医疗保健领域,微藻衍生的化合物在治疗疾病、增强免疫力和应对氧化应激方面显示出巨大潜力。微藻衍生的副淀粉,一种β-葡聚糖,在包括免疫调节和抗癌治疗在内的各种医学应用中已显示出潜力。合成生物学和生物过程工程正在提高微藻的治疗和营养价值,在药物递送和个性化医疗中有应用。为了最大限度地发挥微藻的潜力,需要进一步的研究和开发来解决可扩展性、监管一致性和消费者接受度问题,重点是跨学科合作和可持续实践,以使医疗保健创新与环境保护相一致。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1669/11913682/456b931dd294/fphar-16-1557298-g001.jpg

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