Alwidyan Tahani, Odeh Mohannad, Ibrahim Ameerah Hasan, Harahsheh Eman, Banat Aya
Department of Clinical Pharmacy and Pharmacy Practice, Faculty of Pharmaceutical Sciences, The Hashemite University, Zarqa, Jordan.
Department of Pharmacy, Faculty of Pharmacy, Al-Zaytoonah University of Jordan, Amman, Jordan.
Explor Res Clin Soc Pharm. 2025 Feb 18;18:100578. doi: 10.1016/j.rcsop.2025.100578. eCollection 2025 Jun.
To enhance the impact of pharmacovigilance on drug safety, it must be integrated into the healthcare system. This study aimed to examine community pharmacists' knowledge, attitudes, and practices regarding adverse drug reaction reporting and pharmacovigilance.
A self-administered, cross-sectional questionnaire study was conducted among eligible community pharmacists between July and September 2023. Participants completed online and paper-based questionnaires after providing prior consent. Descriptive and inferential analyses were performed using the Statistical Package for Social Sciences (SPSS, version 28). One-way ANOVA was used to assess the significance of the association between knowledge, attitude, practice scores, and demographic characteristics.
A total of 239 pharmacists completed the questionnaire (response rate of 67.5 %). Of them, 65.3 % were females. Poor knowledge regarding pharmacovigilance was evident in 66.1 % of participants, while only 11 % demonstrated good knowledge. Attitudes were primarily neutral (72.8 %), and practices were categorized as fair for 41.0 % and poor for 31.0 % of pharmacists. Significant factors influencing adverse drug reaction reporting included years of experience ( = 0.012) and awareness of the pharmacovigilance center ( = 0.000). The serious nature of adverse drug reactions was identified as the key facilitator for reporting (40.5 %), while well-documented adverse drug reactions in the literature (21.2 %) and lack of time (19.5 %) were the primary barriers among pharmacists.
This study emphasizes the potential enhancement of adverse drug reaction reporting among community pharmacists by addressing poor knowledge, neutral attitudes, and barriers like time constraints. Targeted educational interventions and structured reporting frameworks are essential to enhance pharmacovigilance and ensure medication safety.
为提高药物警戒对药物安全的影响，必须将其纳入医疗保健系统。本研究旨在调查社区药剂师在药品不良反应报告和药物警戒方面的知识、态度和实践情况。
2023年7月至9月，对符合条件的社区药剂师进行了一项自填式横断面问卷调查研究。参与者在获得事先同意后完成了在线和纸质问卷。使用社会科学统计软件包（SPSS，版本28）进行描述性和推断性分析。单向方差分析用于评估知识、态度、实践得分与人口统计学特征之间关联的显著性。
共有239名药剂师完成了问卷（回复率为67.5%）。其中，65.3%为女性。66.1%的参与者对药物警戒的知识掌握较差，只有11%表现出良好的知识水平。态度主要为中性（72.8%），41.0%的药剂师实践情况被归类为中等，31.0%为较差。影响药品不良反应报告的重要因素包括工作年限（P = 0.012）和对药物警戒中心的了解程度（P = 0.000）。药品不良反应的严重性被确定为报告的关键促进因素（40.5%），而文献中记录良好的药品不良反应（21.2%）和时间不足（19.5%）是药剂师报告的主要障碍。
本研究强调，通过解决知识不足、态度中性以及时间限制等障碍，可以提高社区药剂师报告药品不良反应的可能性。有针对性的教育干预和结构化报告框架对于加强药物警戒和确保用药安全至关重要。
