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在已确诊的原发性开角型青光眼患者中,使用光学相干断层扫描测量黄斑总体积均值。

Mean total macular volume measurement using optical coherence tomography in already diagnosed primary open angle glaucoma patients.

作者信息

Ahmad Hafiz Muhammad, Tahir Muhammad Younis, Chaudhary Muhammad Ajmal, Khan Razaullah

机构信息

Hafiz Muhammad Ahmad, FCPS Consultant Ophthalmologist, Quaid-e-Azam Medical College, Bahawalpur, Pakistan.

Muhammad Younis Tahir, FCPS, FVR Associate Professor Ophthalmology, Quaid-e-Azam Medical College, Bahawalpur, Pakistan.

出版信息

Pak J Med Sci. 2025 Mar;41(3):736-739. doi: 10.12669/pjms.41.3.10102.

DOI:10.12669/pjms.41.3.10102
PMID:40103876
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11911745/
Abstract

OBJECTIVE

To measure the mean total macular volume (MTMV) in primary open angle glaucoma (POAG) patients using optical coherence tomography (OCT).

METHODS

This descriptive cross sectional study was carried out in the department of ophthalmology, Bahawal Victoria Hospital, Bahawalpur from October 2021 to April 2022. A total of 30 patients with POAG, of either gender, between the ages of 20-60 years were included. Patients with secondary glaucoma, having previous intraocular surgery, patients with history of trauma, patients with high myopia and macular disease were excluded. After taking systemic and ophthalmic history, examination of anterior and posterior segments was carried out including best corrected visual acuity (BCVA), intraocular pressure (IOP), central corneal thickness (CCT), gonioscopy, dilated fundus examination of optic nerve and retina, and 30-2° visual field (VF) analysis. OCT was carried out in each patient to measure RNFL thickness and MTMV.

RESULTS

Mean age in our study was 45.50 ± 8.20 years. Majority of these patients 22 (73.33%) were between 41-60 years of age. Among these 30 patients, 20 (66.67%) were male and 10 (33.33%) were females with a male to female ratio of 2:1. MTMV in these POAG patients using OCT was 6.30 ± 1.09 mm.

CONCLUSION

Our study concluded that POAG patients have a reduced MTMV and it can be easily measuresd by a non-invasive technique using OCT. MTMV loss is a useful indicator of documenting glaucoma and monitoring its progression in POAG patients.

摘要

目的

使用光学相干断层扫描(OCT)测量原发性开角型青光眼(POAG)患者的平均黄斑总体积(MTMV)。

方法

本描述性横断面研究于2021年10月至2022年4月在巴哈瓦尔布尔巴哈瓦尔维多利亚医院眼科进行。共纳入30例年龄在20 - 60岁之间的POAG患者,不限性别。排除继发性青光眼患者、既往有眼内手术史的患者、有外伤史的患者、高度近视患者和黄斑疾病患者。在采集全身和眼科病史后,进行眼前节和眼后节检查,包括最佳矫正视力(BCVA)、眼压(IOP)、中央角膜厚度(CCT)、前房角镜检查、视神经和视网膜的散瞳眼底检查以及30 - 2°视野(VF)分析。对每位患者进行OCT检查以测量视网膜神经纤维层(RNFL)厚度和MTMV。

结果

我们研究中的平均年龄为45.50±8.20岁。这些患者中的大多数22例(73.33%)年龄在41 - 60岁之间。在这30例患者中,20例(66.67%)为男性,10例(33.33%)为女性,男女比例为2:1。使用OCT测量的这些POAG患者的MTMV为6.30±1.09立方毫米。

结论

我们的研究得出结论,POAG患者的MTMV降低,并且可以通过使用OCT的非侵入性技术轻松测量。MTMV损失是记录青光眼并监测POAG患者病情进展的有用指标。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/86ac/11911745/c1df50c460fa/PJMS-41-736-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/86ac/11911745/c1df50c460fa/PJMS-41-736-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/86ac/11911745/c1df50c460fa/PJMS-41-736-g001.jpg

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本文引用的文献

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Comparison of changes in retinal nerve fiber layer thickness and intraocular pressure between glaucoma and non-glaucoma patients after phacoemulsification.白内障超声乳化术后青光眼患者与非青光眼患者视网膜神经纤维层厚度及眼压变化的比较。
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Impact of Systemic Comorbidities on Ocular Hypertension and Open-Angle Glaucoma, in a Population from Spain and Portugal.西班牙和葡萄牙人群中全身合并症对高眼压症和开角型青光眼的影响
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