Miyoshi Mirai, Takanashi Rieko, Taguchi Kayoko, Yoshida Tokiko, Kurita Kohei, Shimizu Eiji
Department of Cognitive Behavioral Physiology Graduate School of Medicine, Chiba University Chiba Japan.
Research Center for Child Mental Development Chiba University Chiba Japan.
PCN Rep. 2025 Mar 17;4(1):e70082. doi: 10.1002/pcn5.70082. eCollection 2025 Mar.
Somatic symptom disorder (SSD) is prevalent in primary healthcare settings and is often challenging to diagnose and treat. This study examined the neurodevelopmental and personality traits of individuals with probable SSD.
This cross-sectional study utilized anonymous online surveys. In this study, individuals with a score of 23 or higher on the Somatic Symptom Disorder-B Criteria Scale (SSD-12) were defined as having probable SSD, and individuals with no somatic symptoms and who scored 0 were defined as the healthy control (HC) group. We compared groups regarding neurodevelopmental traits, personality traits, depression, and anxiety using self-report questionnaires and analysis of covariance. In addition, we examined the association between neurodevelopmental traits, emotional problems, and SSD in the probable SSD group using structural equation modeling.
A total of 491 people with probable SSD and 532 age- and sex-matched HCs were analyzed. The scores for somatic symptom severity, depression, generalized anxiety, health anxiety, attention deficit/hyperactivity disorder traits, autism spectrum disorder traits, personality traits, and personality disorder traits showed significant differences between the probable SSD group and the HC group. In the probable SSD group, neurodevelopmental traits positively and directly affected emotional problems and SSD.
Most neurodevelopmental and personality traits were associated with probable SSD. When approaching patients suspected of having SSD, clinicians may consider not only somatic symptoms, but also neurodevelopmental traits, personality traits, depression, and anxiety.
躯体症状障碍（SSD）在基层医疗环境中很常见，其诊断和治疗往往具有挑战性。本研究调查了疑似患有SSD的个体的神经发育和人格特质。
这项横断面研究采用匿名在线调查。在本研究中，躯体症状障碍-B标准量表（SSD-12）得分23分及以上的个体被定义为疑似患有SSD，无躯体症状且得分为0的个体被定义为健康对照组（HC）。我们使用自我报告问卷和协方差分析比较了两组在神经发育特质、人格特质、抑郁和焦虑方面的差异。此外，我们在疑似SSD组中使用结构方程模型研究了神经发育特质、情绪问题和SSD之间的关联。
共分析了491名疑似患有SSD的个体和532名年龄及性别匹配的HC。躯体症状严重程度、抑郁、广泛性焦虑、健康焦虑、注意缺陷/多动障碍特质、自闭症谱系障碍特质、人格特质和人格障碍特质的得分在疑似SSD组和HC组之间存在显著差异。在疑似SSD组中，神经发育特质对情绪问题和SSD有直接的正向影响。
大多数神经发育和人格特质与疑似SSD有关。在诊治疑似患有SSD的患者时，临床医生不仅要考虑躯体症状，还应考虑神经发育特质、人格特质、抑郁和焦虑。
