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声门上喉切除术:系列报告及结果分析

Supraglottic laryngectomy: series report and analysis of results.

作者信息

Burstein F D, Calcaterra T C

出版信息

Laryngoscope. 1985 Jul;95(7 Pt 1):833-6.

PMID:4010424
Abstract

Forty-one consecutive patients who underwent supraglottic laryngectomy at UCLA were reviewed. All of the operations were performed by or under the direct supervision of the same surgeon (T.C.). The majority (68%) had advanced squamous cell carcinoma (Stage III-IV). Approximately one half received radiation therapy as part of planned combined therapy. The overall tumor-free survival, with a two-year minimum follow-up period, was 90%. The most common site of tumor recurrence was neck metastasis. There were four laryngeal recurrences, three of which were salvaged with completion laryngectomy. There was only one completion laryngectomy for severe aspiration. The favorable results in this series are attributed to frozen section control of surgical margins, surgical or radiation therapy treatment of cervical lymph nodes at risk for metastatic disease, and the employment of surgical techniques designed to minimize aspiration.

摘要

对在加州大学洛杉矶分校接受声门上喉切除术的41例连续患者进行了回顾。所有手术均由同一位外科医生(T.C.)实施或在其直接监督下进行。大多数患者(68%)患有晚期鳞状细胞癌(III - IV期)。约一半患者接受了放射治疗,作为计划中的联合治疗的一部分。在至少两年的随访期内,总体无瘤生存率为90%。肿瘤复发最常见的部位是颈部转移。有4例喉部复发,其中3例通过全喉切除术挽救。因严重误吸仅进行了1例全喉切除术。本系列的良好结果归因于手术切缘的冰冻切片控制、对有转移疾病风险的颈部淋巴结进行手术或放射治疗,以及采用旨在尽量减少误吸的手术技术。

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