Suppr超能文献

伴有继发性色素播散的虹膜高原构型:一例报告

Iris Plateau Configuration With Secondary Pigment Dispersion: A Case Report.

作者信息

Alwatban Jawaher, Zendi Nouf A, Walmany Mofi M, Schargel Konrad

机构信息

Ophthalmology, King Khalid Eye Specialist Hospital and Research Center, Riyadh, SAU.

Ophthalmology, Dhahran Eye Specialist Hospital, Dammam, SAU.

出版信息

Cureus. 2025 Feb 16;17(2):e79107. doi: 10.7759/cureus.79107. eCollection 2025 Feb.

Abstract

Pigment dispersion (PD) and plateau iris configuration (PIC) are ocular conditions associated with increased intraocular pressure (IOP) and the development of glaucoma. PD involves the dispersion of pigment epithelium of the iris into the anterior chamber due to contact between the iris and zonular fibers, which subsequently blocks the trabecular meshwork and elevates the IOP. Anatomical variation in PIC narrows the anterior chamber angle. This case report aims to highlight a rare instance of concurrent PD secondary to PIC, conditions that are underreported despite their significant risk of glaucoma-related sequelae. A 64-year-old male presented with blurred vision, pigmented cells in the anterior chamber, and optic disc cupping. Ultrasound biomicroscopy indicated a closed angle with 360-degree anterior rotation of the ciliary body, absence of ciliary sulcus, and chaffing of the posterior iris with the lens capsule and zonules. Collectively, these findings indicated PD secondary to PIC. The condition was managed with phacoemulsification and intraocular lens implantation to address the dual pathology and reduce the risk of glaucoma. The co-occurrenceof PD and PIC necessitates vigilant monitoring and tailored therapeutic approaches to prevent irreversible optic nerve damage and vision loss. Additional studies are necessary to clarify the underlying mechanism and optimize diagnostic and treatment strategies for these complex ocular conditions. Early detection and collaborative management are essential in decreasing the risk of glaucoma and preserving visual function in affected individuals.

摘要

色素播散(PD)和高褶虹膜构型(PIC)是与眼内压(IOP)升高及青光眼发生相关的眼部疾病。色素播散是由于虹膜与悬韧带纤维接触,导致虹膜色素上皮细胞播散至前房,进而阻塞小梁网并使眼内压升高。高褶虹膜构型的解剖变异会使前房角变窄。本病例报告旨在强调一例罕见的继发于高褶虹膜构型的色素播散病例,尽管这两种情况有导致青光眼相关后遗症的重大风险,但报告较少。一名64岁男性出现视力模糊、前房有色素细胞以及视盘杯状凹陷。超声生物显微镜检查显示房角关闭,睫状体360度前转,睫状沟消失,虹膜后表面与晶状体囊膜及悬韧带摩擦。综合这些发现表明为继发于高褶虹膜构型的色素播散。通过白内障超声乳化吸除术及人工晶状体植入术来处理这种双重病变,以降低青光眼风险。色素播散和高褶虹膜构型同时出现需要进行密切监测并采取针对性的治疗方法,以防止不可逆的视神经损伤和视力丧失。有必要开展更多研究以阐明其潜在机制,并优化针对这些复杂眼部疾病的诊断和治疗策略。早期发现和联合管理对于降低青光眼风险及保护受影响个体的视功能至关重要。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验