Figura N, Rossi P, Marri L
Microbiologica. 1985 Apr;8(2):191-6.
The antimicrobial susceptibility of 80 thermophilic Campylobacter strains, 61 C. jejuni and 19 C. coli, isolated from childhood gastroenteritis cases has been studied. Gentamicin and chloramphenicol were effective against all strains; beta-lactams, except carbenicillin and ticarcillin, had on the whole little activity. 26.2% of strains proved to be resistant to tetracycline and 7.5% to erythromycin; erythromycin-resistance was found significantly more often in the species C. coli and always associated to clindamycin-resistance. The high prevalence of strains resistant to erythromycin suggests chloramphenicol and gentamicin as possible alternative drugs in the treatment of life-threatening Campylobacter infections.
对从儿童肠胃炎病例中分离出的80株嗜热弯曲杆菌菌株(61株空肠弯曲杆菌和19株大肠弯曲杆菌)的抗菌药敏性进行了研究。庆大霉素和氯霉素对所有菌株均有效;除羧苄西林和替卡西林外,β-内酰胺类药物总体活性较低。26.2%的菌株对四环素耐药,7.5%的菌株对红霉素耐药;在大肠弯曲杆菌中,红霉素耐药的发生率明显更高,且总是与克林霉素耐药相关。红霉素耐药菌株的高流行率表明,氯霉素和庆大霉素可能是治疗危及生命的弯曲杆菌感染的替代药物。