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亚马逊地区老年人身体功能与肌肉减少症的关系:一项横断面研究。

Relationship between physical function and sarcopenia in the older adults from Amazonas: A cross-sectional study.

作者信息

Lima Alex Barreto de, Henrinques-Neto Duarte, Scott David, de Araújo Pinto André, Dos Santos Ribeiro Gustavo, Peralta Miguel, Miranda Kessketlen Alves, Campos Pedro, Gouveia Elvio Rúbio

机构信息

Course of Physical Education, University of the State of Amazonas, Manaus, Amazonas, Brazil.

Skeletal Muscle Assessment Laboratory (LABSIM), Departament of Physycal Education, School of Tecnology and Sciences, São Paulo State University (UNESP), Presidente Prudente, Brazil.

出版信息

PLoS One. 2025 Mar 19;20(3):e0320079. doi: 10.1371/journal.pone.0320079. eCollection 2025.

Abstract

BACKGROUND

Physical functioning refers to the ability to perform daily living activities, namely basic activities, instrumental, and advanced activities. Poorer performance in these areas may indicate the potential presence of sarcopenia.

OBJECTIVES

To analyze the differences in physical function between older people with and without sarcopenia and to investigate the associations between physical function tests and sarcopenia.

METHODS

A cross-sectional study based on data from older people from the Northern region of Brazil in the year 2018 was conducted. Study participants included 312 older people aged ≥  60 years (64.1% female). Sarcopenia was defined using the updated criteria of the European Working Group on Sarcopenia in Older People (EWGSOP2). Physical functioning was measured using functional physical fitness tests (30-second chair stand test, chair sit-and-reach test, 8-foot Up-and-Go Test, 6-minute walk test, 4-meter gait speed, and the Fullerton Advanced Balance Scale).

RESULTS

Confirmed sarcopenia was detected in 29.2% of participants, but no participant had severe sarcopenia. Most physical function parameters in the crude analysis were associated with confirmed sarcopenia (all p < 0.05), except for the back scratch test. In a model adjusted for sex, age and body mass index, slower 4-meter gait speed (OR = 1.29, 95%CI = 1.08 to 1.54), slower 8-foot up-and-go test time (OR = 1.32, 95%CI = 1.16 to 1.49), greater chair sit-and-reach test (OR = 0.97, 95%CI = 0.94 to 0.99) and higher self-reported Composite Physical Function scores (OR = 0.94, 95%CI = 0.89 to 0.99) were significantly associated with confirmed sarcopenia status.

CONCLUSIONS

EWGSOP2 confirmed sarcopenia is prevalent in older people residing in Brazil's Northern region and is independently associated with slower walking speed and chair rising ability, reduced trunk and lower-limb flexibility, as well as poorer self-reported physical function.

摘要

背景

身体功能是指进行日常生活活动的能力,即基本活动、工具性活动和高级活动。这些方面表现较差可能表明存在肌肉减少症的可能性。

目的

分析有和没有肌肉减少症的老年人在身体功能上的差异,并研究身体功能测试与肌肉减少症之间的关联。

方法

基于2018年巴西北部地区老年人的数据进行了一项横断面研究。研究参与者包括312名年龄≥60岁的老年人(女性占64.1%)。采用老年人肌肉减少症欧洲工作组(EWGSOP2)的更新标准定义肌肉减少症。使用功能性体能测试(30秒坐立试验、椅子坐位体前屈试验、8英尺起身行走试验、6分钟步行试验、4米步态速度和富勒顿高级平衡量表)测量身体功能。

结果

29.2%的参与者被确诊患有肌肉减少症,但没有参与者患有严重肌肉减少症。在粗分析中,除背部抓挠试验外,大多数身体功能参数与确诊的肌肉减少症相关(所有p<0.05)。在对性别、年龄和体重指数进行调整的模型中,4米步态速度较慢(OR=1.29,95%CI=1.08至1.54)、8英尺起身行走试验时间较慢(OR=1.32,95%CI=1.16至1.49)、椅子坐位体前屈试验得分较高(OR=0.97,95%CI=0.94至0.99)以及自我报告的综合身体功能得分较高(OR=0.94,95%CI=0.89至0.99)与确诊的肌肉减少症状态显著相关。

结论

EWGSOP2确诊的肌肉减少症在居住在巴西北部地区的老年人中普遍存在,并且与步行速度减慢、从椅子上起身的能力、躯干和下肢灵活性降低以及自我报告的身体功能较差独立相关。

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本文引用的文献

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Sarcopenia ≠ low muscle mass.肌肉减少症≠低肌肉量。
Eur Geriatr Med. 2023 Apr;14(2):225-228. doi: 10.1007/s41999-023-00760-7.

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