Abdul-Hafez Hamza A, Al Rub Adel Abu, Ali Abd Alkarim, Nassar Laith B, Rashed Mohammed A M, Barakat Mohammed A
Department of Medicine, Faculty of Medicine and Health Sciences, An-Najah National University, Nablus, Palestine.
Department of Medicine, Faculty of Medicine and Health Sciences, An-Najah National University, Nablus, Palestine.
Int J Surg Case Rep. 2025 Apr;129:111168. doi: 10.1016/j.ijscr.2025.111168. Epub 2025 Mar 17.
Prostatic abscess (PA) is a rare urological condition typically associated with predisposing factors such as diabetes, immunosuppression, or prior instrumentation. It is most commonly caused by gram-negative organisms, with methicillin-resistant Staphylococcus aureus (MRSA) being a rare pathogen, even in immunocompromised individuals. Early diagnosis and prompt treatment are important to prevent severe complications.
We report a rare case of a previously healthy 37-year-old male who presented with severe back pain, dysuria, and perineal discomfort persisting for two weeks. Initial evaluation at another facility resulted in a misdiagnosis of urinary tract infection (UTI). At presentation, laboratory tests revealed leukocytosis and elevated C-reactive protein. CT scan showed a large prostatic abscess, measuring of 6 × 7 cm, with necrosis and septations. Blood, urine, and abscess cultures confirmed MRSA. Management involved CT-guided drainage of the abscess and intravenous vancomycin, resulting in complete clinical resolution.
While PA is uncommon, it should be considered in patients with persistent urinary symptoms or back pain unresponsive to standard treatment. MRSA as a causative agent is particularly rare in immunocompetent patients. This case highlights the need for early imaging and culture-directed therapy in atypical presentations.
This report highlights the importance of recognizing prostatic abscess as a differential diagnosis in young, otherwise healthy males with unresolved symptoms. Early intervention and targeted therapy ensure optimal outcomes.
前列腺脓肿(PA)是一种罕见的泌尿系统疾病,通常与糖尿病、免疫抑制或既往器械操作等易感因素相关。其最常见的病因是革兰氏阴性菌,耐甲氧西林金黄色葡萄球菌(MRSA)即使在免疫功能低下的个体中也是罕见病原体。早期诊断和及时治疗对于预防严重并发症很重要。
我们报告一例罕见病例,一名37岁既往健康男性,出现严重背痛、排尿困难和会阴部不适持续两周。在另一家机构的初步评估导致误诊为尿路感染(UTI)。就诊时,实验室检查显示白细胞增多和C反应蛋白升高。CT扫描显示一个6×7厘米的巨大前列腺脓肿,伴有坏死和分隔。血液、尿液和脓肿培养证实为MRSA。治疗包括CT引导下的脓肿引流和静脉注射万古霉素,临床症状完全缓解。
虽然PA不常见,但对于持续存在泌尿系统症状或对标准治疗无反应的背痛患者应考虑该病。MRSA作为病原体在免疫功能正常的患者中尤其罕见。该病例强调了在非典型表现中进行早期影像学检查和培养导向治疗的必要性。
本报告强调了将前列腺脓肿作为年轻、其他方面健康但症状未缓解男性的鉴别诊断的重要性。早期干预和靶向治疗可确保最佳治疗效果。