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用于冠状动脉疾病和心力衰竭的心脏正电子发射断层显像:综述

Cardiac PET Imaging for Coronary Artery Disease and Heart Failure: An Overview.

作者信息

Guduguntla Vinay, Weinberg Richard L

机构信息

Division of Cardiology, Department of Medicine, Feinberg School of Medicine, Northwestern University, 676 North St. Clair Street, Suite 600, Chicago, IL 60611, USA.

Division of Cardiology, Department of Medicine, Feinberg School of Medicine, Northwestern University, 676 North St. Clair Street, Suite 600, Chicago, IL 60611, USA.

出版信息

Heart Fail Clin. 2025 Apr;21(2):175-189. doi: 10.1016/j.hfc.2024.12.002. Epub 2025 Feb 5.

Abstract

Cardiac PET imaging is an important noninvasive modality for the diagnosis and management of heart failure. Cardiac PET myocardial perfusion imaging can identify coronary artery disease with high accuracy and also detect myocardial viability, offering crucial information for the treatment of ischemic cardiomyopathy. Additionally, cardiac PET can help diagnose nonischemic cardiomyopathies including sarcoidosis, amyloidosis, and myocarditis. Improved PET scanner technology combined with emerging radiotracers will, in the future, offer disease-specific molecular imaging that will further assist in the diagnosis, prognosis, and treatment selection for a variety of cardiovascular pathologies.

摘要

心脏正电子发射断层扫描(PET)成像是心力衰竭诊断和管理的重要非侵入性手段。心脏PET心肌灌注成像能够高精度地识别冠状动脉疾病,还能检测心肌存活情况,为缺血性心肌病的治疗提供关键信息。此外,心脏PET有助于诊断包括结节病、淀粉样变性和心肌炎在内的非缺血性心肌病。未来,改进后的PET扫描仪技术与新兴放射性示踪剂相结合,将提供针对特定疾病的分子成像,进一步辅助多种心血管疾病的诊断、预后评估及治疗选择。

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