Plessi Carlotta, Guarino Nino, Vasta Gabriele, Briganti Vito, Fiocca Guido
Pediatric Surgery Unit, Department of Medical, Surgical and Neurological Sciences, S. Maria alle Scotte Hospital, University of Siena, Siena, Italy.
Pediatric Surgery Unit, San Camillo-Forlanini Hospital, C.ne Gianicolense, 87, Rome, 00152, Italy.
World J Urol. 2025 Mar 19;43(1):180. doi: 10.1007/s00345-025-05564-x.
To compare the results of Tauber's antegrade sclerotherapy at different pubertal stages and, notably, to evaluate its feasibility in pre-pubertal age.
We retrospectively reviewed the clinical records of patients that underwent antegrade sclerotherapy at our centre between 2005 and 2019. We divided our population into groups based on pubertal stage according to Tanner's classification. Pre-operative, intra-operative and post-operative data were collected. Finally, we assessed the association between Tanner's stage at surgery, operative characteristics, short-term complications and long-term outcomes.
513 patients were included in our study. Median age was 13 years (range 9-17). 467 (91%) underwent the procedure under local anaesthesia or with mild sedation. Median operative time was 23 min. In 7 cases (1%) conversion was necessary due to intraoperative complications. In 31 cases (6%) we observed minor post-operative complications. Recurrence rate was 3%. Data analyses revealed that there were statistically significant differences among different Tanner's pubertal stages at the intervention in terms of type of anaesthesia (p = 0.009). No difference was found in terms of operative time (p = 0.214), conversion's rate (p = 0.406), postoperative complications (p = 0.159), and clinical outcomes at 1 month (p = 0.916), 6 month (p = 0.112) and at final follow up (p = 0.312).
Tauber's antegrade sclerotherapy is a reliable technique in the treatment of paediatric and adolescent varicocele, regardless of patients' pubertal stage. Although prepubertal patients may need more general anaesthesia, the procedure maintains similar efficacy and complication rates across all age groups.
比较Tauber顺行硬化疗法在不同青春期阶段的治疗效果，尤其是评估其在青春期前年龄段的可行性。
我们回顾性分析了2005年至2019年间在本中心接受顺行硬化疗法的患者的临床记录。根据Tanner分类法，我们将研究人群按青春期阶段分组。收集术前、术中和术后数据。最后，我们评估手术时的Tanner分期、手术特征、短期并发症和长期预后之间的关联。
我们的研究纳入了513例患者。中位年龄为13岁（范围9 - 17岁）。467例（91%）在局部麻醉或轻度镇静下接受了该手术。中位手术时间为23分钟。7例（1%）因术中并发症需要转为其他手术方式。31例（6%）出现轻微术后并发症。复发率为3%。数据分析显示，在干预时，不同Tanner青春期阶段在麻醉类型方面存在统计学显著差异（p = 0.009）。在手术时间（p = 0.214）、转换率（p = 0.406）、术后并发症（p = 0.159）以及1个月（p = 0.916）、6个月（p = 0.112）和最终随访时的临床结局（p = 0.312）方面未发现差异。
Tauber顺行硬化疗法是治疗小儿和青少年精索静脉曲张的可靠技术，无论患者的青春期阶段如何。尽管青春期前患者可能需要更多的全身麻醉，但该手术在所有年龄组中保持相似的疗效和并发症发生率。
