一种由DL-蛋氨酸铬螯合物（Availa® Cr，锌普罗欧洲动物营养公司）组成的饲料添加剂对鲑科鱼类的安全性和有效性
Safety and efficacy of a feed additive consisting of chromium chelate of DL-methionine (Availa® Cr) for salmonids (Zinpro Animal Nutrition Europe, Inc.).
作者信息
Villa Roberto Edoardo, Azimonti Giovanna, Bonos Eleftherios, Christensen Henrik, Durjava Mojca, Dusemund Birgit, Gehring Ronette, Glandorf Boet, Kouba Maryline, López-Alonso Marta, Marcon Francesca, Nebbia Carlo, Pechová Alena, Prieto-Maradona Miguel, Röhe Ilen, Theodoridou Katerina, Aquilina Gabriele, Bories Georges, Gropp Jürgen, Galobart Jaume, Firmino Joana, Ortuño Jordi, Tarrés-Call Jordi, Vettori Maria Vittoria, Pizzo Fabiola
出版信息
EFSA J. 2025 Mar 19;23(3):e9310. doi: 10.2903/j.efsa.2025.9310. eCollection 2025 Mar.
Following a request from the European Commission, EFSA was asked to deliver a scientific opinion on the safety and efficacy of a feed additive consisting of chromium chelate of DL-methionine (Availa® Cr) for salmonids. The EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) concluded that the additive is safe for salmonids at the maximum recommended of 600 mg additive/kg complete feed (corresponding to 0.6 mg Cr/kg complete feed). The use of the additive in animal feed is considered safe for the consumers and the environment. The additive is not an eye nor skin irritant. Due to the presence of nickel, the additive is considered a skin and respiratory sensitiser. Inhalation and dermal exposure are considered a risk. The FEEDAP Panel concludes that the additive may have the potential to be efficacious in improving the performance of salmonids at 200 mg additive/kg complete feed (0.2 mg Cr/kg complete feed).
应欧盟委员会的要求，欧洲食品安全局（EFSA）被要求就一种由DL-蛋氨酸铬螯合物（Availa® Cr）组成的饲料添加剂对鲑鱼的安全性和有效性发表科学意见。欧洲食品安全局动物饲料添加剂和产品或物质专家小组（FEEDAP）得出结论，在最高推荐剂量600毫克添加剂/千克全价饲料（相当于0.6毫克铬/千克全价饲料）下，该添加剂对鲑鱼是安全的。在动物饲料中使用该添加剂被认为对消费者和环境是安全的。该添加剂既不是眼睛刺激性物质也不是皮肤刺激性物质。由于含有镍，该添加剂被认为是一种皮肤和呼吸道致敏剂。吸入和皮肤接触被视为有风险。FEEDAP小组得出结论，在200毫克添加剂/千克全价饲料（0.2毫克铬/千克全价饲料）下，该添加剂可能有提高鲑鱼生长性能的潜力。
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