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迷幻剂与亲社会行为:关于自闭症谱系障碍的一种观点

Psychedelics and Pro-Social Behaviors: A Perspective on Autism Spectrum Disorders.

作者信息

Wang Xue, Lin Cong, Wang Xiaohui

机构信息

Department of Anesthesiology, Lequn Branch, The First Hospital of Jilin University, Changchun 130021, China.

Laboratory of Chemical Biology, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, China.

出版信息

ACS Pharmacol Transl Sci. 2025 Feb 10;8(3):903-906. doi: 10.1021/acsptsci.5c00034. eCollection 2025 Mar 14.

Abstract

Autism Spectrum Disorders (ASD) are complex neurodevelopmental conditions characterized by deficits in social interaction, communication, and repetitive behaviors. This viewpoint explores the potential mechanisms through which psychedelics such as lysergic acid diethylamide (LSD), psilocybin, and 3,4-methylenedioxymethamphetamine (MDMA) may positively influence pro-social behaviors, focusing on their implications for individuals with ASD.

摘要

自闭症谱系障碍(ASD)是复杂的神经发育疾病,其特征为社交互动、沟通及重复行为方面存在缺陷。本观点探讨了诸如麦角酸二乙酰胺(LSD)、裸盖菇素和3,4-亚甲基二氧甲基苯丙胺(摇头丸)等迷幻剂可能对亲社会行为产生积极影响的潜在机制,重点关注其对自闭症谱系障碍患者的影响。

相似文献

1
Psychedelics and Pro-Social Behaviors: A Perspective on Autism Spectrum Disorders.迷幻剂与亲社会行为:关于自闭症谱系障碍的一种观点
ACS Pharmacol Transl Sci. 2025 Feb 10;8(3):903-906. doi: 10.1021/acsptsci.5c00034. eCollection 2025 Mar 14.
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本文引用的文献

1
Can psychedelics improve well-being in autism?迷幻药能改善自闭症患者的幸福感吗?
Science. 2024 Dec 20;386(6728):1333. doi: 10.1126/science.adv4102. Epub 2024 Dec 19.
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Autism Diagnosis Among US Children and Adults, 2011-2022.美国儿童和成人自闭症诊断,2011-2022 年。
JAMA Netw Open. 2024 Oct 1;7(10):e2442218. doi: 10.1001/jamanetworkopen.2024.42218.
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Psilocybin desynchronizes the human brain.裸盖菇素使人类大脑去同步化。
Nature. 2024 Aug;632(8023):131-138. doi: 10.1038/s41586-024-07624-5. Epub 2024 Jul 17.
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Therapeutic mechanisms of psychedelics and entactogens.迷幻剂和快感增强剂的治疗机制。
Neuropsychopharmacology. 2024 Jan;49(1):104-118. doi: 10.1038/s41386-023-01666-5. Epub 2023 Jul 24.
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Psychedelics reopen the social reward learning critical period.迷幻剂重新开启社会奖励学习的关键期。
Nature. 2023 Jun;618(7966):790-798. doi: 10.1038/s41586-023-06204-3. Epub 2023 Jun 14.
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Possible psychedelic therapeutic mechanism.可能的迷幻治疗机制。
Science. 2023 Feb 17;379(6633):642-643. doi: 10.1126/science.adg2989. Epub 2023 Feb 16.

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