Ke Qiaozhen, Li Yin, Weng Huasong, Chen Baohua, Wang Jiaying, Zhao Ji, Jiang Pengxin, Xu Peng, Zhou Tao
College of the Environment and Ecology, Xiamen University, Xiamen, China.
State Key Laboratory of Mariculture Breeding, College of Ocean and Earth Sciences, Xiamen University, Xiamen, China.
Front Genet. 2025 Mar 5;16:1540305. doi: 10.3389/fgene.2025.1540305. eCollection 2025.
Large yellow croaker is an economically important carnivorous marine aquaculture fish in China with high protein requirements. Current fish meal - based feeds face issues like high cost and resource depletion, while plant protein sources have potential but also controversies. To explore this, a 120 - day feeding trial was conducted with a standard commercial feed (CF) and a modified feed (PF) where 70% of fish meal was replaced by plant protein. Results showed no significant growth performance differences between the two groups. Transcriptome analysis identified 557 and 308 differentially expressed genes in the liver and intestine respectively. GO and KEGG enrichment analyses indicated their association with immune response, lipid metabolism, and signal transduction. Five key genes related to metabolism and immune regulation were also found. These findings underscore the potential of integrating plant protein into fish diets, which could significantly enhance sustainable practices in global aquaculture while reducing reliance on fish meal. Emphasizing this transition is crucial for fostering environmental sustainability and supporting the future of aquaculture.
大黄鱼是中国一种具有重要经济价值的肉食性海水养殖鱼类，对蛋白质需求量很高。目前以鱼粉为基础的饲料面临成本高和资源枯竭等问题，而植物蛋白源虽有潜力但也存在争议。为探究此问题，进行了一项为期120天的投喂试验，采用标准商业饲料（CF）和改良饲料（PF），其中70%的鱼粉被植物蛋白替代。结果表明两组之间的生长性能无显著差异。转录组分析分别在肝脏和肠道中鉴定出557个和308个差异表达基因。基因本体（GO）和京都基因与基因组百科全书（KEGG）富集分析表明它们与免疫反应、脂质代谢和信号转导有关。还发现了五个与代谢和免疫调节相关的关键基因。这些发现强调了将植物蛋白整合到鱼类饲料中的潜力，这可以显著加强全球水产养殖的可持续做法，同时减少对鱼粉的依赖。强调这一转变对于促进环境可持续性和支持水产养殖的未来至关重要。
