Heyman I, Rang H P
Neurosci Lett. 1985 May 1;56(1):69-75. doi: 10.1016/0304-3940(85)90442-2.
Microelectrode recordings from the somata of rat dorsal root ganglion (DRG) cells were used to correlate their electrophysiological characteristics with sensitivity to locally applied capsaicin. Of the 80 cells tested, 17 responded to capsaicin by a rapid depolarization. These cells had low axonal conduction velocities (less than 1.4 m/s) and long duration action potentials, characteristic of C-cells. Some C-cells did not respond to capsaicin, and no A-cells, which had high conduction velocities and brief action potentials, did so. The effect of capsaicin on the current-voltage curve of C-cells suggested that it produced a conductance increase as well as a change in delayed rectification.
通过对大鼠背根神经节（DRG）细胞胞体进行微电极记录，将其电生理特性与对局部应用辣椒素的敏感性相关联。在测试的80个细胞中，17个细胞对辣椒素产生快速去极化反应。这些细胞具有低轴突传导速度（小于1.4米/秒）和长时程动作电位，这是C类细胞的特征。一些C类细胞对辣椒素无反应，而具有高传导速度和短动作电位的A类细胞均无此反应。辣椒素对C类细胞电流-电压曲线的影响表明，它不仅导致电导增加，还引起延迟整流的变化。
