Wakawa Ibrahim Abdu, Musami Umar Baba, Kwairanga Suleiman Hamidu, Ogualili Placidus Nwankuba, Mahmood Mohammed Yusuf, Fugu Muhammad Abba, Gimba Mohammed Mala, Allamin Muktar Mohammed, Abbas Zaharadeen Umar, Sunkani Muhammad Kawu, Yaganami Zainab Bukar, Kadau Fatima Mustapha, Sani Nasir Muhammad, Danmallam Peter, Nanjul Luka, Babazau Larema, Muhammad Zaid, Goni Baba Waru, Machina Babagana Kundi, Karch Celeste M, Udeh-Momoh Chinedu, Karikari Thomas K, Onyike Chiadi U, Maina Mahmoud Bukar
Department of Medical Services, Federal Neuropsychiatric Hospital, Maiduguri, Borno, Nigeria.
Department of Mental Health, College of Medical Sciences, University of Maiduguri, Maiduguri, Borno, Nigeria.
Alzheimers Dement. 2025 Mar;21(3):e14538. doi: 10.1002/alz.14538.
Dementia prevalence is increasing in sub-Saharan Africa, potentially due to population growth and aging. Resource-constrained settings such as Northeastern Nigeria face challenges in dementia management.
We assessed dementia burden and management at the Federal Neuropsychiatric Hospital Maiduguri, the only neuropsychiatric facility in Northeastern Nigeria. This retrospective analysis included patient records from 1999 to 2023 for individuals 60 year of age and older with a dementia diagnosis.
Of the 1216 cases reported, Alzheimer's disease (60.5%) was the most common subtype, followed by vascular dementia (24.5%). Hypertension (41.6%) was the most frequent comorbidity. Memory loss was present in all cases, whereas behavioral symptoms like agitation presented in some cases. Treatments included cognitive enhancers (donepezil), supplements (gingko biloba), and non-drug therapies (psychoeducation).
The increasing burden of dementia at this sole facility highlights the urgent need for targeted interventions and further research to understand the underlying factors contributing to dementia in this population.
Dementia trends and management in a neuropsychiatric facility serving over 26 million people in Northeastern Nigeria. Alzheimer's disease accounted for 60.5% of the dementia cases reported, with hypertension as the leading comorbidity. There is an urgent need for improved diagnostic tools and health care infrastructure to address dementia in resource-constrained settings. The findings lay the foundation for developing a dementia cohort as part of the Northern Nigeria Dementia Research Group.
撒哈拉以南非洲地区的痴呆症患病率正在上升，这可能是由于人口增长和老龄化所致。像尼日利亚东北部这样资源有限的地区在痴呆症管理方面面临挑战。
我们在迈杜古里联邦神经精神病医院评估了痴呆症负担及管理情况，该医院是尼日利亚东北部唯一的神经精神病设施。这项回顾性分析纳入了1999年至2023年期间60岁及以上被诊断为痴呆症患者的病历。
在报告的1216例病例中，阿尔茨海默病（60.5%）是最常见的亚型，其次是血管性痴呆（24.5%）。高血压（41.6%）是最常见的合并症。所有病例均存在记忆力减退，而部分病例出现了如激动等行为症状。治疗方法包括认知增强剂（多奈哌齐）、补充剂（银杏叶）和非药物疗法（心理教育）。
这家唯一设施中痴呆症负担的增加凸显了针对性干预措施和进一步研究的迫切需求，以了解导致该人群痴呆症的潜在因素。
尼日利亚东北部一家为超过2600万人服务的神经精神病设施中的痴呆症趋势及管理情况。阿尔茨海默病占报告的痴呆症病例的60.5%，高血压是主要合并症。在资源有限的环境中，迫切需要改进诊断工具和医疗保健基础设施以应对痴呆症。这些发现为作为尼日利亚北部痴呆症研究小组一部分建立痴呆症队列奠定了基础。
