Artan Yağmur, Sezgin Gökhan, Bulut İrem, Yildirim Yasemin
Faculty of Health Sciences, Nursing Department, Ardahan University, Merkez, Post Box 75000, Ardahan, Turkey.
Bone Marrow Transplantation Unit, İzmir City Hospital, İzmir, Turkey.
Support Care Cancer. 2025 Mar 20;33(4):303. doi: 10.1007/s00520-025-09367-z.
This study aimed to assess the use of complementary and integrative medicine among cancer patients in Turkey for managing fatigue and to examine the moderating effect of disease duration on the relationship between fatigue levels and patients' attitudes toward complementary and integrative medicine.
A cross-sectional study was conducted with 231 cancer patients recruited from a chemotherapy center in western Turkey. Participants completed sociodemographic forms, the Holistic Complementary and Alternative Medicine Questionnaire, and the Visual Analog Scale for Fatigue. Data were analyzed using linear regression and moderation analysis.
Among the participants, 38.5% reported using complementary and integrative medicine to manage fatigue, with biologically based treatments such as vitamin supplements and herbal tea being the most common. Regression analysis showed that younger age (p < 0.05), longer disease duration (p = 0.005), absence of complementary and integrative medicine-related complications (p < 0.001), and higher fatigue levels (p < 0.001) were significant predictors of positive attitudes toward complementary and integrative medicine. Additionally, disease duration moderated the relationship between fatigue levels and attitudes toward complementary and integrative medicine, with longer disease duration strengthening the association (B = - 0.269, SE = 0.078, p = 0.001).
The findings suggest that fatigue and prolonged disease duration significantly influence cancer patients' attitudes toward complementary and integrative medicine. Given the increasing use of complementary and integrative medicine, healthcare professionals should provide evidence-based guidance to ensure its safe and effective use. Future research should explore the long-term effects of complementary and integrative medicine on cancer-related fatigue.
This study highlights the importance of addressing cancer-related fatigue and recognizing the growing use of complementary and integrative medicine among cancer patients.
Patients were invited to complete questionnaires. Investigators explained the study's objectives and content and addressed any concerns raised during data collection.
本研究旨在评估土耳其癌症患者使用补充和整合医学来管理疲劳的情况，并检验疾病持续时间对疲劳水平与患者对补充和整合医学态度之间关系的调节作用。
对从土耳其西部一家化疗中心招募的231名癌症患者进行了一项横断面研究。参与者填写了社会人口学表格、整体补充和替代医学问卷以及疲劳视觉模拟量表。使用线性回归和调节分析对数据进行分析。
在参与者中，38.5%的人报告使用补充和整合医学来管理疲劳，最常见的是基于生物的治疗方法，如维生素补充剂和花草茶。回归分析表明，年龄较小（p < 0.05）、疾病持续时间较长（p = 0.005）、没有补充和整合医学相关并发症（p < 0.001）以及疲劳水平较高（p < 0.001）是对补充和整合医学持积极态度的显著预测因素。此外，疾病持续时间调节了疲劳水平与对补充和整合医学态度之间的关系，疾病持续时间越长，这种关联越强（B = -0.269，SE = 0.078，p = 0.001）。
研究结果表明，疲劳和疾病持续时间延长显著影响癌症患者对补充和整合医学的态度。鉴于补充和整合医学的使用日益增加，医疗保健专业人员应提供循证指导，以确保其安全有效使用。未来的研究应探讨补充和整合医学对癌症相关疲劳的长期影响。
本研究强调了应对癌症相关疲劳以及认识到癌症患者中补充和整合医学使用日益增加的重要性。
邀请患者填写问卷。研究人员解释了研究的目的和内容，并解决了数据收集过程中提出的任何问题。
