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减压性颅骨切除术和颅骨扩张术后颅内高压患者脑容量增加的比较。

Comparison of brain volume increase in patients with intracranial hypertension after decompressive craniectomy and expansion craniotomy.

作者信息

Berra Luigi Valentino, Rubiano Andres, Cedrone Guido, Capobianco Mattia, Bassani Andrea, Santoro Antonio

机构信息

Policlinico Umberto I, Rome, Italy.

Sapienza University of Rome, Rome, Italy.

出版信息

Neurosurg Rev. 2025 Mar 21;48(1):311. doi: 10.1007/s10143-025-03440-1.

Abstract

Intracranial hypertension is a critical condition often resulting from traumatic brain injury or malignant middle cerebral artery ischemia, necessitating surgical intervention when conservative treatments fail. This study compares the efficacy of decompressive craniectomy (DC) and expansion craniotomy (EC) in managing cerebral edema. Sixty-three patients, 52 undergoing DC and 11 undergoing EC, were evaluated for changes in brain volume, midline shift, and other key parameters using pre- and post-operative CT scans. Results indicated that brain volume increased significantly more in the EC group (100 ± 51 cm³) compared to the DC group (72 ± 51 cm³, p < 0.05). Both techniques effectively reduced midline displacement, but EC showed a superior capacity for brain expansion. The findings suggest that EC, which raises the cranial operculum to reduce soft tissue tension and provide hemostatic effects, may offer advantages over DC by allowing greater decompression and reducing the risk of complications such as epidural hematomas. These results support the potential of EC as a promising alternative to DC for treating intracranial hypertension. Future research should investigate long-term outcomes to further validate these findings.

摘要

颅内高压是一种危急情况,常由创伤性脑损伤或大脑中动脉恶性缺血引起,当保守治疗失败时需要进行手术干预。本研究比较了减压性颅骨切除术(DC)和扩大颅骨切开术(EC)在处理脑水肿方面的疗效。对63例患者进行了评估,其中52例行DC,11例行EC,通过术前和术后CT扫描观察脑容量、中线移位及其他关键参数的变化。结果表明,与DC组(72±51cm³)相比,EC组脑容量增加更为显著(100±51cm³,p<0.05)。两种技术均能有效减少中线移位,但EC在脑扩张方面表现出更强的能力。研究结果表明,EC通过抬高颅盖以减轻软组织张力并产生止血效果,可能比DC具有更大优势,能实现更大程度的减压并降低硬膜外血肿等并发症的风险。这些结果支持了EC作为治疗颅内高压的一种有前景的替代DC方法的潜力。未来研究应调查长期结果以进一步验证这些发现。

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