Niehoff J M, Baltatzis P A
Postgrad Med. 1985 Jul;78(1):117-9, 123. doi: 10.1080/00325481.1985.11699058.
Noncardiogenic pulmonary edema induced by salicylate toxicity is becoming a well-recognized entity. However, the diagnosis can be easily missed early in the disease course. We report here adult respiratory distress syndrome (ARDS) in a 54-year-old man found to have salicylate toxicity one day after admission to the alcohol detoxification service at a community hospital. He had been taking one enteric-coated aspirin tablet twice a day for more than one year. He also had a 40 pack-year history of cigarette smoking. The list in any standard medical text of factors triggering ARDS is quite lengthy. Over the past few years, salicylate toxicity has been added to this list. As the case reported here illustrates, it is most important that salicylate toxicity be considered in the differential diagnosis for any patient with acute onset of pulmonary edema and normal cardiac function.
水杨酸盐中毒所致非心源性肺水肿正成为一种广为人知的病症。然而,在病程早期诊断很容易被遗漏。我们在此报告一名54岁男性的成人呼吸窘迫综合征(ARDS),该患者在社区医院戒酒服务中心入院一天后被发现存在水杨酸盐中毒。他每天服用两次肠溶阿司匹林片,已持续一年多。他还有40年的吸烟史,吸烟量相当于40包年。任何标准医学文献中引发ARDS的因素列表都相当长。在过去几年里,水杨酸盐中毒也被列入了该列表。正如这里报告的病例所示,对于任何急性肺水肿且心功能正常的患者,在鉴别诊断中考虑水杨酸盐中毒至关重要。