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静脉血栓栓塞的发生及其对新冠病毒肺炎住院成人患者的影响:快速系统评价

Development of venous thromboembolism and its impact on hospitalized adults with covid-19: rapid systematic review.

作者信息

Rocha Andressa Pereira, Sanchez João Gabriel

机构信息

Hcor, São Paulo, SP, Brasil.

Universidade de Brasília - UnB, Brasília, DF, Brasil.

出版信息

J Vasc Bras. 2025 Mar 14;24:e20240073. doi: 10.1590/1677-5449.202400732. eCollection 2025.

Abstract

The association between COVID-19 and coagulation disorders has been discussed since the onset of the pandemic. Four years into the pandemic, it is crucial to organize the findings and evidence accumulated thus far. The objective of this study was to review and synthesize the available scientific evidence regarding the relationship between COVID-19 and development of venous thromboembolism (VTE). A rapid systematic review was conducted by searching two electronic databases, selecting systematic review articles that assessed the association between COVID-19 and development of VTE, such as deep vein thrombosis (DVT) or pulmonary embolism (PE). The studies indicated that hospitalized COVID-19 patients are at greater risk of developing VTE, especially those admitted to intensive care units (ICUs). Elevated D-dimer levels and male gender were also associated with increased risks.

摘要

自新冠疫情爆发以来,新冠病毒与凝血功能障碍之间的关联就一直被人们讨论。在疫情爆发四年之际,整理迄今积累的研究结果和证据至关重要。本研究的目的是回顾和综合关于新冠病毒与静脉血栓栓塞症(VTE)发生之间关系的现有科学证据。通过检索两个电子数据库进行了快速系统评价,选择了评估新冠病毒与VTE发生之间关联的系统评价文章,如深静脉血栓形成(DVT)或肺栓塞(PE)。研究表明,新冠病毒住院患者发生VTE的风险更高,尤其是那些入住重症监护病房(ICU)的患者。D-二聚体水平升高和男性也与风险增加有关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c24a/11924586/2b29b9d9dfbc/jvb-24-e20240073-g01-en.jpg

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