Gowda Shreya K, Errichetti Enzo, Behera Biswanath, Thakur Vishal, Garg Sonika, Sahu Deepak Kumar, Sethy Madhusmita, Ayyanar Pavithra
Department of Dermatology and Venereology, All India Institute of Medical Sciences, Bhubaneswar, India.
Institute of Dermatology, "Santa Maria della Misericordia" University Hospital, Piazzale Santa Maria della Misericordia, Udine, Italy.
Dermatol Pract Concept. 2025 Jan 30;15(1):4481. doi: 10.5826/dpc.1501a4481.
Lichen planopilaris (LPP) and frontal fibrosing alopecia (FFA) are primary scarring alopecias that few authors consider the same entity, and some consider them different. Only a few reviews focus on trichoscopic findings in delineating these two alopecias.
We describe and summarize the trichoscopic features of both conditions.
We performed an extensive literature search using the PubMed and Google Scholar databases. The Chi-square test was applied to compare the trichoscopic features in LPP and FFA. P-values less than 0.05 were considered statistically significant.
Out of 60 articles, 33 (16 LPP, 17 FFA) were considered for quantitative analysis due to availability in English literature with full text. We found that peripilar cylindrical casts and perifollicular erythema with arborizing vessels were predominant features suggesting early LPP. In contrast, yellow dots, perifollicular erythema, and scattered pigmentation suggested active FFA. Shiny-white area was seen in both groups in the inactive stages. The target arrangement of blue-grey dots, milky-red areas, and irregularly arranged white fibrotic dots were seen in late LPP, and black dots, lonely hairs, and loss of vellus hairs were detected in the later stages of FFA. Features such as blue-grey structureless areas, blue-white veil, and variability in morphologies of hair shafts were not significantly different between the two groups.
This article provides a comprehensive literature review on the trichoscopic features of LPP and FFA, including comparing the similarities, differences, and peculiarities of both conditions.
扁平苔藓样毛发角化病(LPP)和额部纤维性秃发(FFA)是原发性瘢痕性脱发,很少有作者认为它们是同一实体,而一些人则认为它们不同。只有少数综述关注在区分这两种脱发时的毛囊镜检查结果。
我们描述并总结这两种疾病的毛囊镜特征。
我们使用PubMed和谷歌学术数据库进行了广泛的文献检索。应用卡方检验比较LPP和FFA的毛囊镜特征。P值小于0.05被认为具有统计学意义。
在60篇文章中,由于英文文献中有全文可供使用,33篇(16篇LPP,17篇FFA)被纳入定量分析。我们发现,毛囊周围圆柱状痂皮和伴有树枝状血管的毛囊周围红斑是提示早期LPP的主要特征。相比之下,黄点、毛囊周围红斑和散在色素沉着提示活跃期FFA。在非活动期,两组均可见亮白色区域。晚期LPP可见蓝灰色点的靶样排列、乳红色区域和不规则排列的白色纤维化点,FFA后期可见黑点、孤立毛发和毳毛缺失。两组之间蓝灰色无结构区域、蓝白色面纱和毛干形态变异等特征无显著差异。
本文对LPP和FFA的毛囊镜特征进行了全面的文献综述,包括比较两种疾病的异同点和特殊之处。