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毛囊镜检在扁平苔藓性毛发角化病和额部纤维化性秃发累及眉毛情况中的评估及有效性:一项病例对照研究

Assessment and Validity of Trichoscopy for Eyebrow Involvement in Lichen Planopilaris and Frontal Fibrosing Alopecia: A Case-Control Study.

作者信息

Kelati Awatef, Halli Wassim, Chiheb Soumiya

机构信息

Dermatology Department, University Hospital Cheikh Khalifa, and the University Hospital Mohammed VI Faculty of Medicine, Mohammed VI University of Health and Sciences (UM6SS), Casablanca, Morocco.

Non-invasive Skin Imaging Group of the French Society of Dermatology.

出版信息

Dermatol Pract Concept. 2024 Oct 30;14(4):e2024277. doi: 10.5826/dpc.1404a277.

DOI:10.5826/dpc.1404a277
PMID:39652942
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11620180/
Abstract

INTRODUCTION

Few publications are available on eyebrow trichoscopy in patients with alopecia areata and frontal fibrosing alopecia (FFA).

OBJECTIVE

To investigate the validity of using trichoscopy to examine eyebrow involvement in patients with lichen planopilaris (LPP) and FFA.

METHODS

In this case-control study, 109 patients with eyebrow involvement in LPP and FFA (cases) and with acquired hair disorders of the eyebrows (controls) were included.

RESULTS

Trichoscopy was highly specific and sensitive for the diagnosis of LPP and FFA. Trichoscopic features significantly associated with LPP were peripilar scaling, peripilar pigmentation, broken hairs, peripilar white halos, diffuse empty follicles, and vellus hair. Localized peripilar erythema and empty follicles were significantly associated with the diffuse form of LPP and the zigzag type of FFA. Yellow dots, dystrophic hairs, hair regrowth in different directions, and diffuse empty follicles were associated with LPP activity and FFA severity.

LIMITATIONS

The retrospective nature of the statistical analysis.

CONCLUSIONS

Trichoscopy is a valid tool for evaluating eyebrow involvement in LPP and FFA. Thus, it could help increase the diagnostic accuracy and predict the prognosis of eyebrow hair loss at an early stage.

摘要

引言

关于斑秃和额部纤维性脱发(FFA)患者的眉毛皮肤镜检查的文献较少。

目的

探讨使用皮肤镜检查扁平苔藓性秃发(LPP)和FFA患者眉毛受累情况的有效性。

方法

在这项病例对照研究中,纳入了109例眉毛受累的LPP和FFA患者(病例组)以及获得性眉毛毛发疾病患者(对照组)。

结果

皮肤镜检查对LPP和FFA的诊断具有高度特异性和敏感性。与LPP显著相关的皮肤镜特征包括毛囊周脱屑、毛囊周色素沉着、断发、毛囊周白色晕、弥漫性空毛囊和毳毛。局限性毛囊周红斑和空毛囊与LPP的弥漫型和FFA的锯齿型显著相关。黄点、营养不良性毛发、不同方向的毛发再生和弥漫性空毛囊与LPP的活动度和FFA的严重程度相关。

局限性

统计分析的回顾性性质。

结论

皮肤镜检查是评估LPP和FFA患者眉毛受累情况的有效工具。因此,它有助于提高诊断准确性并在早期预测眉毛脱发的预后。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/db8e/11620180/7909b9c35d01/dp1404a277g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/db8e/11620180/da8acdb867a1/dp1404a277g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/db8e/11620180/7909b9c35d01/dp1404a277g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/db8e/11620180/da8acdb867a1/dp1404a277g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/db8e/11620180/7909b9c35d01/dp1404a277g002.jpg

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本文引用的文献

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Acquired causes of eyebrow and eyelash loss: A review and approach to diagnosis and treatment.获得性眉毛和睫毛缺失的原因:诊断和治疗方法的回顾。
Australas J Dermatol. 2023 Feb;64(1):28-40. doi: 10.1111/ajd.13947. Epub 2022 Nov 1.
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Eyebrow and Eyelash Alopecia: A Clinical Review.眉毛和睫毛脱发:临床综述。
Am J Clin Dermatol. 2023 Jan;24(1):55-67. doi: 10.1007/s40257-022-00729-5. Epub 2022 Oct 2.
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Trichoscopy beyond scalp. A narrative review.头皮之外的毛发镜检查:一项叙述性综述
Int J Dermatol. 2023 Mar;62(3):416-427. doi: 10.1111/ijd.16226. Epub 2022 May 5.
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Lichen planopilaris and frontal fibrosing alopecia: review and update of diagnostic and therapeutic features.瘢痕性类扁平苔藓和额部纤维性脱发:诊断和治疗特征的回顾与更新。
An Bras Dermatol. 2022 May-Jun;97(3):348-357. doi: 10.1016/j.abd.2021.08.008. Epub 2022 Apr 2.
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Isolated hair loss on the eyebrow: five cases with trichoscopic features.眉毛孤立性脱发:五例具有毛发镜特征的病例。
An Bras Dermatol. 2022 May-Jun;97(3):372-375. doi: 10.1016/j.abd.2021.04.015. Epub 2022 Mar 7.
6
Development of Clinician-Reported Outcome (ClinRO) and Patient-Reported Outcome (PRO) Measures for Eyebrow, Eyelash and Nail Assessment in Alopecia Areata.斑秃患者眉毛、睫毛和指甲评估的临床医生报告结局(ClinRO)和患者报告结局(PRO)指标的制定。
Am J Clin Dermatol. 2020 Oct;21(5):725-732. doi: 10.1007/s40257-020-00545-9.
7
Trichoscopy findings of frontal fibrosing alopecia on the eyebrows: A study of 151 cases.眉毛部位额部纤维性脱发的毛发镜检查结果:151 例研究。
J Am Acad Dermatol. 2021 Nov;85(5):1130-1134. doi: 10.1016/j.jaad.2019.12.023. Epub 2019 Dec 17.
8
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J Am Acad Dermatol. 2020 Dec;83(6):1659-1667. doi: 10.1016/j.jaad.2019.11.006. Epub 2019 Nov 9.
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J Cosmet Dermatol. 2020 Jun;19(6):1404-1408. doi: 10.1111/jocd.13167. Epub 2019 Sep 21.