Dunn F
Radiat Environ Biophys. 1985;24(2):131-9. doi: 10.1007/BF01229819.
Inactivation of Chinese hamster V79 cells in vitro by a temperature elevation to 43 degrees C and with Couette shear flow was investigated. The shear stresses were chosen to mimic those produced by ultrasound of approximately 3 MHz and 3 W/cm2 within the chambers employed by earlier investigators studying ultrasonic inactivation of cellular processes. The combined shear and thermal stresses produced survival curves exhibiting a summating effect among these two stresses and remarkably similar to the ultrasound/thermal survival curves.
研究了在体外通过将温度升高至43摄氏度并施加库埃特剪切流来使中国仓鼠V79细胞失活的情况。所选择的剪切应力旨在模拟早期研究超声对细胞过程失活的研究人员在所用腔室内约3兆赫兹和3瓦/平方厘米的超声所产生的剪切应力。剪切应力和热应力共同作用产生的存活曲线显示出这两种应力之间的叠加效应，并且与超声/热存活曲线非常相似。
