Cheema A H, Hooshmand-Rad P
Res Vet Sci. 1985 May;38(3):292-5.
Mature Fasciola gigantica obtained from naturally infected cattle were surgically transferred into the gallbladders of six fluke-free goats. Two of the goats died at two and 19 weeks and the remaining four were slaughtered at 12, 48, 48 and 80 weeks after the transfer. Nine of 20 transferred F gigantica were recovered from the gallbladder and common hepatic duct of the experimental goats. The walls of gallbladders and bile ducts were thickened by epithelial proliferation, fibrosis and mononuclear cell infiltration. Large numbers of globule leucocytes were present in the epithelium of gallbladders and common hepatic ducts as well as in minute intrahepatic bile ducts. Very few mast cells were observed in these locations. Globule leucocytes in two goats were positive for argentaffin reaction with Gomori hexamine silver stain. The proliferative cholecystitis in experimental goats was similar to adenomatous cholecystitis in cattle naturally infected with fascioliasis. Globule leucocytes had no obvious deleterious effects on the parasites.
从自然感染的牛体内获取的成熟巨片形吸虫，通过手术移植到6只未感染吸虫的山羊胆囊中。其中2只山羊分别在移植后2周和19周死亡，其余4只在移植后12周、48周、48周和80周被宰杀。从实验山羊的胆囊和肝总管中回收了20只移植的巨片形吸虫中的9只。胆囊和胆管壁因上皮细胞增生、纤维化和单核细胞浸润而增厚。胆囊、肝总管以及肝内小胆管的上皮中有大量球形白细胞。在这些部位观察到的肥大细胞极少。用Gomori六胺银染色法，两只山羊的球形白细胞嗜银反应呈阳性。实验山羊的增殖性胆囊炎与自然感染片形吸虫病的牛的腺瘤性胆囊炎相似。球形白细胞对寄生虫没有明显的有害影响。
