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采用模块化大假体行膝关节融合术作为感染性膝关节肿瘤假体患者肢体挽救手术:1例病例报告

Knee arthrodesis with modular megaprosthesis as salvage procedure for the limb following in a patient with an infected knee tumor prosthesis: A case report.

作者信息

Olivieri Rodrigo, Franulic Nicolás, Amoedo Felipe, Laso José I, Rojas Tania, Rojas Carlos, Gaggero Nicolás

机构信息

Orthopaedic Surgeon, Knee Unit, Orthopaedics Department, Hospital del Trabajador, Santiago, Chile.

Head of Knee Unit, Orthopaedic Department, Hospital del Trabajador, Santiago, Chile.

出版信息

Trauma Case Rep. 2025 Feb 27;56:101152. doi: 10.1016/j.tcr.2025.101152. eCollection 2025 Apr.

Abstract

INTRODUCTION

The management of periprosthetic knee infections is a complex event, especially in the context of megaprostheses. An accepted option in these cases is knee arthrodesis, aiming to salvage the limb with acceptable and pain-free functionality. We present a successful case of knee arthrodesis using a hybrid model of modular nail-prosthesis in a patient with massive bone stock loss following the removal of an infected tumor-type prosthesis.

CASE PRESENTATION

A 65-year-old male patient with a chronic periprosthetic infection related to a resection prosthesis implanted 5 years earlier, experiencing knee stiffness and presenting a massive bone stock deficit after prosthesis removal. Initial management involved an osteo-cement spacer and antibiotics, along with a transarticular external fixator. Subsequently, knee arthrodesis was performed using a hybrid model of modular nail-prosthesis, coupled with targeted antibiotic treatment. The arthrodesis was deemed successful, with a pain-free limb and no signs of infection recurrence at the 52-month follow-up.

CONCLUSION

In the scenario of infection and massive bone stock deficit, knee arthrodesis using intramedullary devices such as nails, megaprostheses, or hybrids is an alternative that can be successful if accompanied by appropriate medical-surgical management of the infection. This approach allows for earlier functional recovery compared to other techniques.

摘要

引言

人工膝关节周围感染的处理是一个复杂的问题,尤其是在使用大型假体的情况下。在这些病例中,一种被认可的选择是膝关节融合术,旨在挽救肢体并使其具有可接受的、无痛的功能。我们报告了一例成功的膝关节融合术病例,该病例采用模块化钉-假体混合模型,用于一名在移除感染的肿瘤型假体后出现大量骨量丢失的患者。

病例介绍

一名65岁男性患者,患有与5年前植入的切除假体相关的慢性人工关节周围感染,膝关节僵硬,假体移除后出现大量骨量缺损。初始治疗包括使用骨水泥间隔物和抗生素,以及跨关节外固定架。随后,采用模块化钉-假体混合模型进行膝关节融合术,并进行针对性的抗生素治疗。融合术被认为是成功的,在52个月的随访中,肢体无痛,没有感染复发的迹象。

结论

在感染和大量骨量缺损的情况下,使用髓内装置(如钉、大型假体或混合体)进行膝关节融合术是一种可行的选择,如果同时对感染进行适当的内科-外科处理,则可能成功。与其他技术相比,这种方法能够使功能更早恢复。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5353/11930096/b09d1c4e236e/gr1.jpg

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